Synthesis of 1-(1-adamantyl)-2-hydroxy-3-amino-3-R-propanones

被引：5
|
作者：
Kozlov, NG [1 ]
Korotyshova, GP [1 ]
机构：
[1] Natl Acad Sci Belarus, Inst Phys Organ Chem, Minsk, BELARUS
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2002年 / 72卷 / 12期
关键词：
Hydrogen; Hydrogen Peroxide; Ketone; Epoxidation; Piperidine;
D O I：
10.1023/A:1023467413472
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Previously unknown cis-1-(1-adamantyl)-2,3-epoxy-3-R-propanones were highly selectively obtained by epoxidation of alpha,beta-unsaturated ketones with hydrogen peroxide in alkaline medium. The regio-selectivity of the epoxide ring cleavage with amines (piperidine and morpholine) was studied.
引用
收藏
页码：1934 / 1937
页数：4
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