Dynamic adsorption and desorption behavior of protein on carbonate-containing apatite

被引：2
|
作者：
Kanno, Toru [1 ]
Inaba, Morito [1 ]
Sendai, Toru [1 ]
Tada, Kiyoshi [1 ]
Horiuchi, Jun-ichi [1 ]
Akazawa, Toshiyuki [2 ]
Itabashi, Koji [2 ]
机构：
[1] Kitami Inst Technol, Dept Biotechnol & Environm Chem, Kitami, Hokkaido 0908507, Japan
[2] Hokkaido Ind Res Inst, Kita Ku, Sapporo, Hokkaido 0600819, Japan
来源：
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN | 2010年 / 118卷 / 1378期
关键词：
Carbonate ion-containing apatite; Drug-delivery carrier; Adsorption and desorption behavior of protein; Flow system; Bovine serum albumin; BOVINE SERUM-ALBUMIN; HYDROXYAPATITE; DELIVERY; MICROSPHERES; INSULIN; RELEASE;
D O I：
10.2109/jcersj2.118.545
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
A new flow experimental system was employed in order to obtain relevant information about the capability of hydroxyapatite as a drug-delivery carrier in vitro rather than in batch systems. Using our system, we were able to estimate and monitor continuously both the adsorbed and desorbed amounts of protein and the dynamic adsorption and desorption behavior, indicating that this system is a promising technique for evaluating the drug-release properties of ceramic materials. (C) 2010 The Ceramic Society of Japan. All rights reserved.
引用
收藏
页码：545 / 547
页数：3
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