Molecular and cytogenetic remission in a case of subtype M4E acute myelogenous leukemia with minimal monochemotherapy: high sensitivity or spontaneous remission?

被引：6

作者：

Martelli, MP ^{[1
]}

Latagliata, R ^{[1
]}

Spadea, A ^{[1
]}

Avvisati, G ^{[1
]}

Mancini, M ^{[1
]}

Romano, A ^{[1
]}

Luzi, G ^{[1
]}

Petti, MC ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Biotecnol Cellulari & Ematol, Rome, Italy

来源：

EUROPEAN JOURNAL OF HAEMATOLOGY | 2000年 / 65卷 / 03期

关键词：

acute myelogenous leukemia; spontaneous remission;

D O I：

10.1034/j.1600-0609.2000.9c220.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Complete remission was observed in an adult patient with acute myelogenous leukemia after minimal monochemotherapy. Remission occurred after a severe febrile pneumonia and was accompanied by cytogenetic and molecular remission. The hypothesis of spontaneous remission was raised, even if a high sensitivity to low-dose cytostatics cannot be excluded. Such spontaneous complete remissions, often associated with bacterial infections and blood transfusions, are extremely rare, and are usually of short duration. Previous cases are summarized, and the role of etiologic factors is discussed.

引用

页码：203 / 206

页数：4

共 21 条

[21] Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Versus Conventional Chemotherapy in Patients with Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS) Attaining Complete Remission (CRI) Post Induction Chemotherapy: a Retrospective Case Control Study.
Efebera, Yvonnr A.
Kantarjian, Hagop M.
Andersson, Borje
Pierce, Sherry
Silva, Leandro De Padua
Ravandi, Farhad
Giralt, Sergio A.
Borthalcur, Gautain
Champlin, Richard
De Lima, Marcos
BLOOD, 2008, 112 (11) : 411 - 411

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