Escherichia coli or E. coli is the dominant pathogen in Urinary Tract Infections (UTIs) in more than 80 % of the cases. Laboratory urine culture is the standard detection method which is expensive and time consuming. This paper studies the possibility of using a capacitive sensor to diagnose UTIs. Experimental tests were carried out to investigate the touch sensor's response to artificially prepared E. coli sample. The capacitive touch sensor gave a consistent result that could be used to design a portable diagnostic device for early detection of UTIs. An exponential response was observed to increasing volume (up to 100 microliter) and E. coli presence in the sample. When the volume reached 100 microliter, the capacitance in average RAW Count Difference value became constant. Urine sample mixed with liquid E. coli gave the highest capacitance change (in average RAW Count Difference value) and the sensitivity at 100 microliter was found to be 22 counts per picofarad (pF).
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Stanford Univ, Dept Bioengn, 443 Via Ortega, Stanford, CA 94305 USA
Univ Oxford, Rudolf Peierls Ctr Theoret Phys, Oxford1 Keble Rd, Oxford OX1 3NP, EnglandStanford Univ, Dept Bioengn, 443 Via Ortega, Stanford, CA 94305 USA
Mathijssen, Arnold J. T. M.
Figueroa-Morales, Nuris
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Univ Paris Diderot, Sorbonne Univ, PSL Res Univ, PMMH,UMR 7636,CNRS,ESPCI, 7-9 Quai St Bernard, F-75005 Paris, France
Penn State Univ, Dept Biomed Engn, University Pk, PA 16802 USAStanford Univ, Dept Bioengn, 443 Via Ortega, Stanford, CA 94305 USA
Figueroa-Morales, Nuris
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Junot, Gaspard
Clement, Eric
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Univ Paris Diderot, Sorbonne Univ, PSL Res Univ, PMMH,UMR 7636,CNRS,ESPCI, 7-9 Quai St Bernard, F-75005 Paris, FranceStanford Univ, Dept Bioengn, 443 Via Ortega, Stanford, CA 94305 USA
Clement, Eric
Lindner, Anke
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Univ Paris Diderot, Sorbonne Univ, PSL Res Univ, PMMH,UMR 7636,CNRS,ESPCI, 7-9 Quai St Bernard, F-75005 Paris, FranceStanford Univ, Dept Bioengn, 443 Via Ortega, Stanford, CA 94305 USA
Lindner, Anke
Zoettl, Andreas
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Univ Oxford, Rudolf Peierls Ctr Theoret Phys, Oxford1 Keble Rd, Oxford OX1 3NP, England
Univ Paris Diderot, Sorbonne Univ, PSL Res Univ, PMMH,UMR 7636,CNRS,ESPCI, 7-9 Quai St Bernard, F-75005 Paris, France
TU Wien, Inst Theoret Phys, Wiedner Hauptstr 8-10, Vienna, AustriaStanford Univ, Dept Bioengn, 443 Via Ortega, Stanford, CA 94305 USA
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Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, ItalyUniv Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy
Bianchi, S.
Saglimbeni, F.
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Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, ItalyUniv Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy
Saglimbeni, F.
Lepore, A.
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Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, ItalyUniv Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy
Lepore, A.
Di Leonardo, R.
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Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy
CNR, NANOTEC, Soft & Living Matter Lab, I-00185 Rome, ItalyUniv Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy