Diastereoselective synthesis and structure of spirooxindole derivatives

被引:21
|
作者
Risitano, F
Grassi, G
Foti, F
Bruno, G
Rotondo, A
机构
[1] Univ Messina, Dipartimento Chim Organ & Biol, I-98166 Messina, Italy
[2] Univ Messina, Dipartimento CHim Inorgan Analit & Struttura Mol, I-98166 Messina, Italy
关键词
D O I
10.3987/COM-02-9694
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Spiroindolinonisoxazolines (4 and 5h) are prepared from (E)-1 or (Z)-3-arylidene-2-oxindoles (2) by nitrile oxide cycloaddition reactions. Only one regioisomer is detected in all cases, and the observed complete diastereoselection is established by unambigous structural assignments.
引用
收藏
页码:857 / 863
页数:7
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