Simulation studies of vapor bubble generation by short-pulse lasers

被引：2

作者：

Amendt, P ^{[1
]}

London, RA ^{[1
]}

Strauss, M ^{[1
]}

Glinsky, ME ^{[1
]}

Maitland, DJ ^{[1
]}

Celliers, PM ^{[1
]}

Visuri, SR ^{[1
]}

Bailey, DS ^{[1
]}

Young, DA ^{[1
]}

Ho, D ^{[1
]}

Lin, CP ^{[1
]}

Kelly, MW ^{[1
]}

机构：

[1] Univ Calif Lawrence Livermore Natl Lab, Livermore, CA 94550 USA

来源：

LASER-TISSUE INTERACTION, TISSUE OPTICS, AND LASER WELDING III, PROCEEDINGS OF | 1998年 / 3195卷

关键词：

short-pulse laser; hydrodynamics; bubble; shock wave; melanosome;

D O I：

10.1117/12.297909

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Formation of vapor bubbles is characteristic of many applications of short-pulse lasers in medicine. An understanding of the dynamics of vapor bubble generation is useful for developing and optimizing laser-based medical therapies. To this end, experiments in vapor bubble generation with laser light deposited in an aqueous dye solution near a fiber-optic tip have been performed. Numerical hydrodynamic simulations have been developed to understand and extrapolate results from these experiments. Comparison of two-dimensional simulations with the experiment shows excellent agreement in tracking the bubble evolution. Another regime of vapor bubble generation is short-guise laser interactions with melanosomes. Strong shock generation and vapor bubble generation are common physical features of this interaction. A novel effect of discrete absorption by melanin granules within a melanosome is studied as a possible role in previously reported high Mach number shocks [Lin and Kelly, SPIE 2391, 294 (1995)].

引用

页码：259 / 272

页数：14

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