Adenomatous Polyp With Intestinal Metaplasia of the Esophagus (Barrett Esophagus) in a Dog

被引：18
|
作者：
Gibson, C. J. [1 ]
Parry, N. M. A. [1 ]
Jakowski, R. M. [1 ]
Cooper, J. [2 ]
机构：
[1] Tufts Univ, Cummings Sch Vet Med, Dept Biomed Sci, Sect Pathol, North Grafton, MA 01536 USA
[2] Tufts Univ, Cummings Sch Vet Med, Dept Clin Sci, North Grafton, MA 01536 USA
来源：
VETERINARY PATHOLOGY | 2010年 / 47卷 / 01期
关键词：
adenomatous polyp; Barrett esophagus; canine; metaplasia; standard poodle; COLUMNAR METAPLASIA; ADENOCARCINOMA; CANCER; REFLUX; MODEL;
D O I：
10.1177/0300985809352973
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Multiple endoscopic biopsy specimens of esophageal mucosa were received from a 13-year-old castrated male standard Poodle. The dog was presented for painful swallowing. Endoscopically, the distal aspect of the esophagus was inflamed with a polypoid mass that protruded into the esophageal lumen. Histologically, the stratified squamous epithelium overlying the mass and lining the adjacent esophageal mucosa was replaced by papillary projections covered by columnar epithelium with goblet cells supported by a fibrous stroma. This article reports a case of spontaneous esophageal adenomatous polyp with intestinal metaplasia (Barrett esophagus) and reviews the pathogenesis of esophageal metaplasia and adenocarcinoma.
引用
收藏
页码：116 / 119
页数：4
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