Genome editing in clinical genetics: points to consider-a statement of the American College of Medical Genetics and Genomics

被引:13
|
作者
Watson, Michael S. [1 ]
机构
[1] Amer Coll Med Genet & Genom, Bethesda, MD USA
关键词
biotechnology; CRISPR/Cas9; gene editing; genetic engineering; gene drives;
D O I
10.1038/gim.2016.195
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Disclaimer: These recommendations are designed primarily as an educational resource for medical geneticists and other health-care providers, to help them provide quality medical genetic services. Adherence to these recommendations does not necessarily assure a successful medical outcome. These recommendations should not be considered inclusive of all proper procedures and tests or exclusive of other procedures and tests that are reasonably directed to obtaining the same results. In determining the propriety of any specific procedure or test, the geneticist should apply his or her own professional judgment to the specific clinical circumstances presented by the individual patient or specimen. It may be prudent, however, to document in the patient's record the rationale for any significant deviation from these recommendations.
引用
收藏
页码:723 / 724
页数:2
相关论文
共 50 条
  • [21] Incidental detection of acquired variants in germline genetic and genomic testing: a points to consider statement of the American College of Medical Genetics and Genomics (ACMG)
    Chao, Elizabeth C.
    Astbury, Caroline
    Deignan, Joshua L.
    Pronold, Melissa
    Reddi, Honey V.
    Weitzel, Jeffrey N.
    GENETICS IN MEDICINE, 2021, 23 (07) : 1179 - 1184
  • [22] Scope of practice: a statement of the American College of Medical Genetics and Genomics (ACMG)
    Watson, Michael S.
    GENETICS IN MEDICINE, 2015, 17 (09)
  • [23] Correspondence on " Clinical utility of polygenic risk scores for embryo selection: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)" " by Grebe et al
    Widen, Erik
    Lello, Louis
    Eccles, Jennifer
    Marin, Diego
    Treff, Nathan R.
    GENETICS IN MEDICINE, 2024, 26 (08)
  • [24] Points to consider in the detection of germline structural variants using next-generation sequencing: A statement of the American College of Medical Genetics and Genomics (ACMG)
    Raca, Gordana
    Astbury, Caroline
    Behlmann, Andrea
    De Castro, Mauricio J.
    E. Hickey, Scott
    Karaca, Ender
    Lowther, Chelsea
    Rooney Riggs, Erin
    A. Seifert, Bryce
    C. Thorland, Erik
    Deignan, Joshua L.
    GENETICS IN MEDICINE, 2023, 25 (02)
  • [25] Clinical utility of genetic and genomic services: a position statement of the American College of Medical Genetics and Genomics
    Watson, Michael
    GENETICS IN MEDICINE, 2015, 17 (06) : 505 - 507
  • [26] Clinical Genetics in the age of Genomics and Genome editing
    Veitia, R. A.
    CLINICAL GENETICS, 2016, 89 (01) : 3 - 4
  • [27] Correspondence on "Clinical utility of polygenic risk scores for embryo selection: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)" by Grebe et al Reply
    Grebe, Theresa A.
    Khushf, George
    Greally, John M.
    Turley, Patrick
    Foyouzi, Nastaran
    Rabin-Havt, Sara
    Berkman, Benjamin
    Pope, Kathleen
    Vatta, Matteo
    Kaur, Shagun
    GENETICS IN MEDICINE, 2024, 26 (08)
  • [28] DNA-based screening and population health: a points to consider statement for programs and sponsoring organizations from the American College of Medical Genetics and Genomics (ACMG)
    Murray, Michael F.
    Giovanni, Monica A.
    Doyle, Debra L.
    Harrison, Steven M.
    Lyon, Elaine
    Manickam, Kandamurugu
    Monaghan, Kristin G.
    Rasmussen, Sonja A.
    Scheuner, Maren T.
    Palomaki, Glenn E.
    Watson, Michael S.
    GENETICS IN MEDICINE, 2021, 23 (06) : 989 - 995
  • [29] Points to consider in the reevaluation and reanalysis of genomic test results: A statement of the American College of Medical Genetics and Genomics (ACMG) (vol 21, pg 1267, 2019)
    Reddi, Honey, V
    Avenarius, Matthew R.
    Bean, Lora J. H.
    Best, Hunter
    Guha, Saurav
    Kang, Benjamin E.
    Scharfe, Curt
    Seifert, Bryce A.
    Wakeling, Erin
    GENETICS IN MEDICINE, 2024, 26 (05)
  • [30] The use of fetal exome sequencing in prenatal diagnosis: a points to consider document of the American College of Medical Genetics and Genomics (ACMG)
    Monaghan, Kristin G.
    Leach, Natalia T.
    Pekarek, Dawn
    Prasad, Priya
    Rose, Nancy C.
    GENETICS IN MEDICINE, 2020, 22 (04) : 675 - 680