Single-fiber electromyography during menstrual exacerbation and ovulatory suppression in MuSK antibody-positive myasthenia gravis

被引：11
|
作者：
Stickler, David E.
Stickler, Laura L.
机构：
[1] Med Univ S Carolina, Div Neurol, Dept Neurosci, Charleston, SC 29464 USA
[2] Med Univ S Carolina, Dept Obstet & Gynecol, Charleston, SC 29425 USA
来源：
MUSCLE & NERVE | 2007年 / 35卷 / 06期
关键词：
electromyography; estrogen; jitter; menstrual; MuSK;
D O I：
10.1002/mus.20734
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We report a patient with muscle-specific tyrosine kinase (MuSK) anti body-positive myasthenia gravis who experienced worsening of myasthenic weakness associated with alterations in estrogen and progesterone levels during the administration of oral contraceptive therapy. Single-fiber electromyography was performed to document changes in neuromuscular transmission associated with the clinical exacerbation and subsequent resolution of the menstrual exacerbation and clinical improvement experienced with continuous monophasic oral contraceptive therapy. The potential long-term benefit of ovulatory suppression in MuSK anti body-positive myasthenia gravis is discussed.
引用
收藏
页码：808 / 811
页数：4
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