Scalarane metabolites of the nudibranch Glossodoris rufomarginata and its dietary sponge from the South China Sea

被引:31
|
作者
Gavagnin, M
Mollo, E
Docimo, T
Guo, YW
Cimino, G
机构
[1] CNR, Ist Chim Biomol, I-80078 Pozzuoli, Na, Italy
[2] Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China
来源
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 12期
关键词
D O I
10.1021/np040087s
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Chemical investigation of the nudibranch Glossodoris rufomarginata and its sponge prey provided additional evidence of the trophic relationship between Glossodoris nudibranchs and scalarane-containing sponges. Scalaradial (1) and its deacetyl derivative 2 were found to be the main components of the extract of the sponge, whereas a series of related scalaranes (3-7), probably derived from dietary scalaradial, were isolated from the mollusk. Two new scalarane sesterterpenes (5 and 6), exhibiting a keto functionalization at C-12, were characterized by spectroscopic methods and chemical correlations.
引用
收藏
页码:2104 / 2107
页数:4
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