Direct Synthesis of Dihydrobenzo[a]carbazoles via Palladium-Catalyzed Domino Annulation of Indoles

被引：34
|
作者：
Jafarpour, Farnaz [1 ]
Hazrati, Hamideh [1 ]
机构：
[1] Univ Tehran, Sch Chem, Univ Coll Sci, Tehran 141556455, Iran
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 2-3期
基金：
美国国家科学基金会;
关键词：
benzo[a]carbazoles; bromoalkylindoles; domino reactions; one-step synthesis; palladium catalyst; ALKYLATION/DIRECT ARYLATION REACTION; NITROGEN-CONTAINING HETEROCYCLES; THROMBOPOIETIN TPO RECEPTOR; SMALL-MOLECULE AGONISTS; DERIVATIVES; COMPLEXES; SEQUENCE; LIGANDS; CYCLOPALLADATION; BINDING;
D O I：
10.1002/adsc.200900725
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A straightforward one-step synthesis of annulated indoles via palladium-catalyzed, norbornene-mediated sequential intermolecular aryl ortho-alkylation/intramolecular indole c-h activation has been devised. This method provides ail efficient route to a wide variety of substituted 6,1.1-dihydro-5 H-benzo[a]carbazoles from readily accessible 3-bromoalkylindoles and iodoarenes.
引用
收藏
页码：363 / 367
页数：5
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