Economic Decision Model for First-Time Traumatic Patellar Dislocations in Adolescents

被引:22
|
作者
Nwachukwu, Benedict U. [1 ,2 ]
So, Conan [1 ,3 ]
Schairer, William W. [1 ,2 ]
Shubin-Stein, Beth E. [1 ,2 ]
Strickland, Sabrina M. [1 ,2 ]
Green, Daniel W. [1 ,2 ]
Dodwell, Emily R. [1 ,2 ]
机构
[1] Hosp Special Surg, 535 E 70th St, New York, NY 10021 USA
[2] Hosp Special Surg, Dept Orthopaed Surg, 535 East 70th St, New York, NY 10021 USA
[3] Univ Maryland, Sch Med, Baltimore, MD 21201 USA
来源
AMERICAN JOURNAL OF SPORTS MEDICINE | 2017年 / 45卷 / 10期
关键词
cost-utility analysis; patellar dislocation; medial patellofemoral ligament; quality of life; cost; COST-UTILITY ANALYSES; SURGICAL-TREATMENT; CHILDREN; SURGERY; HEALTH; RECOMMENDATIONS; ARTHROPLASTY; INSTABILITY; RESILIENCE; MANAGEMENT;
D O I
10.1177/0363546517703347
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Background: The surgical management of traumatic patellar dislocations in adolescents is associated with a lower rate of recurrent dislocations compared with nonoperative care. However, the attendant cost of surgery and the quality-of-life benefit of a surgical treatment strategy are unclear. Purpose: To compare the cost-utility of 3 management strategies for acute first-time patellar dislocations in adolescents: (1) nonoperative treatment only, (2) initial nonoperative treatment with surgery only for recurrent dislocations, and (3) immediate surgery. Study Design: Economic and decision analysis; Level of evidence, 2. Methods: A 10-year state-transition Markov model was constructed to compare the cost-utility of the 3 index treatment protocols. Utilities used to define health states were derived from a telephone interview of 60 adolescents with a history of acute patellar dislocations. The probability of transition between each health state was informed by the available literature. Direct costs were estimated using a statewide ambulatory surgery database, and indirect costs were estimated based on parental lost productivity. Effectiveness was expressed in quality-adjusted life years (QALYs). The principal outcome measure was the incremental cost-effectiveness ratio (ICER). Results: In the base case for our model, nonoperative treatment only was the least costly ($ 7300) but also the least effective (5.30 QALYs); initial nonoperative treatment with delayed surgery cost $ 10,500 for a 5.93 QALY benefit, while immediate surgical treatment cost $ 17,100 and provided 6.32 QALY benefits. Compared with nonoperative treatment only, initial nonoperative treatment with delayed surgery was associated with an ICER of $ 5100 per QALY. When immediate surgery was compared with a strategy of delayed surgery, immediate surgery provided incremental benefits at an ICER of $ 17,000 per QALY. The model was sensitive to the probability of surgical versus nonoperative treatment to achieve a full return to preinjury activity versus an intermediate lower state. When the probability of achieving a full return to preinjury activity with initial nonoperative treatment exceeds 47.5% (compared with 34.2% in the base case), then initial nonoperative treatment with delayed surgery is preferred to immediate surgery. Similarly, when the probability of achieving a full return to full preinjury activity with surgery falls below 51% (compared with 64% in the base case), then delayed surgery after initial nonoperative treatment is preferred. Conclusion: Immediate surgery and delayed surgical treatment are both cost-effective treatment options; however, immediate surgical treatment provides the highest QALY gains within a 10- year time horizon. Our model sensitivity analysis highlights the role of optimizing functional and quality-of-life benefits in the treatment of acute traumatic patellar dislocations. These findings have implications for clinical guidelines and policy decisions relating to adolescent patellar dislocations.
引用
收藏
页码:2267 / 2275
页数:9
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