Freezing of Gait in Parkinsonism and its Potential Drug Treatment

被引：23
|
作者：
Zhang, Li-Li [1 ,2 ]
Canning, S. Duff [3 ]
Wang, Xiao-Ping [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Dept Neurol, Shanghai Peoples Hosp 1, Shanghai 200080, Peoples R China
[2] Nanjing Med Univ, Nanjing Brain Hosp, Dept Neurol, Nanjing 210029, Jiangsu, Peoples R China
[3] Univ Toronto, Dept Psychol, Toronto, ON M5S 1A1, Canada
来源：
CURRENT NEUROPHARMACOLOGY | 2016年 / 14卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Drug treatment; freezing of gait; Levodopa; Parkinson's disease; Parkinsonism; BOTULINUM TOXIN INJECTIONS; INTRAVENOUS AMANTADINE; DOPAMINE TRANSPORTER; CALF MUSCLES; PD PATIENTS; DISEASE; METHYLPHENIDATE; STIMULATION; LEVODOPA; IMPROVEMENT;
D O I：
10.2174/1570159X14666151201190040
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3,4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.
引用
收藏
页码：302 / 306
页数：5
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