Simulating genetic networks made easy: network construction with simple building blocks

被引:3
|
作者
Vercruysse, S [1 ]
Kuiper, M [1 ]
机构
[1] State Univ Ghent VIB, Dept Plant Syst Biol, B-9052 Ghent, Belgium
关键词
D O I
10.1093/bioinformatics/bth478
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present SIM-plex, a genetic network simulator with a very intuitive interface in which a user can easily specify interactions as simple 'if-then' statements. The simulator is based on the mathematical model of Piecewise Linear Differential Equations (PLDEs). With PLDEs, genetic interactions are approximated as acting in a switch-like manner.
引用
收藏
页码:269 / 271
页数:3
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