Selecting killers: the line between life and death

被引：2
|
作者：
Nicholson, LB
Kuchroo, VK
机构：
[1] Brigham & Womens Hosp, Ctr Neurol Dis, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
来源：
NATURE IMMUNOLOGY | 2000年 / 1卷 / 03期
关键词：
D O I：
10.1038/79726
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
How do T cells that are specific for pancreatic islet cell antigens cause diabetes? A recent paper in Nature provides evidence from NOD mice that the killer T cells responsible increase their avidity as the disease progresses-removing the high avidity clones prevents disease.
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页码：192 / 194
页数：3
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