Glycals in the stereoselective synthesis of triterpene 2-deoxy-α-L-glycosides under conditions of acidic catalysis

被引：19

作者：

Flekhter, OB ^{[1
]}

Baltina, LA ^{[1
]}

Tolstikov, GA ^{[1
]}

机构：

[1] Russian Acad Sci, Ufa Res Ctr, Inst Organ Chem, Ufa 450054, Russia

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 07期

关键词：

D O I：

10.1021/np990273b

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

3 beta-Hydroxy triterpenes of the oleanane, ursane, and lupane types were successfully glycosylated with acetylated L-glucal and L-rhamnal under conditions of acidic catalysis (anhydrous cation-exchange resin and LiBr). The 2-deoxy- and 2,6-dideoxy-alpha-L-carabino-hexopyranosides (1-5) were stereoselectively prepared in 83-90% yields, following deacetylation under mild conditions, which led to the target triterpene 2-deoxy-alpha-L-glycosides (6-10).

引用

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页码：992 / 994

页数：3

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