Stimulation of vagus nerve modifies negative chronotropic and hypotensive effects of adenosine

被引：1

作者：

Ziyatdinova, NI ^{[1
]}

Gainuffin, AA

Ziganshin, AU

Zefirov, TL

机构：

[1] Kazan State Pedag Univ, Dept Anat, Kazan, Russia

[2] Kazan State Pedag Univ, Dept Physiol, Kazan, Russia

[3] Kazan State Pedag Univ, Dept Human Hlth Protect, Kazan, Russia

[4] Kazan State Med Univ, Dept Pharmacol, Kazan, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2004年 / 137卷 / 05期

关键词：

heart; adenosine; vagus nerve; arterial pressure; rat;

D O I：

10.1023/B:BEBM.0000038142.47230.2b

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The effects of electrical stimulation of the vagus nerve on the negative chronotropic and hypotensive effects of adenosine were studied on adult rats. Intravenous injection of adenosine to control rats significantly reduced the heart rate and induced a transient blood pressure drop followed its increase. Preliminary electrical stimulation of the right vagus nerve reduced the magnitude and duration of adenosine-induced bradycardia and changed the dynamics of adenosine-induced arterial pressure perturbations.

引用

页码：425 / 427

页数：3

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