Large Scale Process for the Production and Purification of Lentiviral Vectors for Clinical Applications

被引:0
|
作者
Bellintani, Francesca [1 ]
Piacenza, Luca [1 ]
Birolo, Roberto Sciarretta [1 ]
Martelli, Andrea [1 ]
Addamo, Roberto Raffaele [1 ]
Vallanti, Giuliana [1 ]
Fracchia, Sergio [1 ]
Salomoni, Monica [1 ]
Aiuti, Alessandro [1 ,2 ]
Biffi, Alessandra [2 ]
Galy, Anne [3 ]
Merten, Otto-Wilhelm [3 ]
Benati, Claudia [1 ]
Ziliotto, Raul [1 ]
Bordignon, Claudio [1 ]
Naldini, Luigi [2 ,4 ]
Radrizzani, Marina [1 ]
机构
[1] MolMed SpA, Milan, Italy
[2] San Raffaele Telethon Istitute Gene Therapy, Milan, Italy
[3] Genethon, Evry, France
[4] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Milan, Italy
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:S276 / S276
页数:1
相关论文
共 50 条
  • [31] Production of Therapeutically Relevant Lentiviral Vectors for Clinical Studies
    Dettmann, Johann-Christoph
    Schaser, Thomas
    MOLECULAR THERAPY, 2017, 25 (05) : 330 - 330
  • [32] Development of Large-Scale Downstream Processing for Lentiviral Vectors
    Valkama, Anniina J.
    Oruetxebarria, Igor
    Lipponen, Eevi M.
    Leinonen, Hanna M.
    Kayhty, Piia
    Hynynen, Heidi
    Turkki, Vesa
    Malinen, Joonas
    Miinalainen, Tuukka
    Heikura, Tommi
    Parker, Nigel R.
    Yla-Herttuala, Seppo
    Lesch, Hanna P.
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2020, 17 : 717 - 730
  • [33] To Develop a Lentiviral Packaging Cell Line for Scale-Up Production of Lentiviral Vectors
    Thomas, Amelia H.
    Slauson, Sarah
    Seidel, Stacie
    Veres, Gabor
    Ryu, Byoung Y.
    MOLECULAR THERAPY, 2014, 22 : S282 - S283
  • [34] Dual Tangential Flow Purification Improves Downstream Processing of Large Scale Clinical-Grade Preparations of Lentiviral Vectors for Phase I/II Clinical Trials
    Wohlfahrt, Martin E.
    Woodle, Douglas
    Manger, Ronald
    Adams, Amie
    Olsen, Philip
    Beard, Brian C.
    Sahai, Suchit
    Till, Brian G.
    Kiem, Hans-Peter
    MOLECULAR THERAPY, 2018, 26 (05) : 152 - 153
  • [35] Optimized production and concentration of lentiviral vectors containing large inserts
    Al Yacoub, Nadya
    Romanowska, Malgorzata
    Haritonova, Natalie
    Foerster, John
    JOURNAL OF GENE MEDICINE, 2007, 9 (07): : 579 - 584
  • [36] Production and purification of lentiviral vectors generated in 293T suspension cells with baculoviral vectors
    H P Lesch
    A Laitinen
    C Peixoto
    T Vicente
    K-E Makkonen
    L Laitinen
    J T Pikkarainen
    H Samaranayake
    P M Alves
    M J T Carrondo
    S Ylä-Herttuala
    K J Airenne
    Gene Therapy, 2011, 18 : 531 - 538
  • [37] Production and purification of lentiviral vectors generated in 293T suspension cells with baculoviral vectors
    Lesch, H. P.
    Laitinen, A.
    Peixoto, C.
    Vicente, T.
    Makkonen, K-E
    Laitinen, L.
    Pikkarainen, J. T.
    Samaranayake, H.
    Alves, P. M.
    Carrondo, M. J. T.
    Yla-Herttuala, S.
    Airenne, K. J.
    GENE THERAPY, 2011, 18 (06) : 531 - 538
  • [38] Implementation of a Reproducible and Effective Process for the GMP Production of Lentiviral Vectors
    Noguiez-Hellin, Patricia
    Merten, Otto-Wilhelm
    Fauchille, Sylvain
    Laroudie, Nicolas
    Dugue, Celine
    Charrier, Sabine
    Zanta-Boussif, Maria-Antonietta
    Chautard, Helene
    Caizergues, Didier
    Radrizzani, Marina
    Aiuti, Alessandro
    Naldini, Luigi
    Galy, Anne
    MOLECULAR THERAPY, 2009, 17 : S18 - S19
  • [39] A practical method for production and purification of 3rd generation HIV based lentiviral vectors for In vivo applications
    Olgun, H. B.
    Balci, M. K.
    Sanlioglu, S.
    HUMAN GENE THERAPY, 2017, 28 (12) : A65 - A65
  • [40] Development of improved production and purification protocols for preclinical grade lentiviral vectors.
    Kutner, R.
    Reiser, J.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2007, 55 (01) : S264 - S264