The evolutionary conservation of the mammalian peroxidase genes

被引：10
|
作者：
Sakamaki, K
Ueda, T
Nagata, S
机构：
[1] Kyoto Univ, Inst Virus Res, Sakyo Ku, Kyoto 6068507, Japan
[2] Kyoto Univ, Grad Sch Biostudies, Dept Anim Dev & Physiol, Kyoto, Japan
[3] Osaka City Univ, Sch Med, Dept Internal Med 3, Osaka 545, Japan
[4] Osaka Univ, Sch Med, Dept Genet, Osaka, Japan
来源：
CYTOGENETIC AND GENOME RESEARCH | 2002年 / 98卷 / 01期
关键词：
D O I：
10.1159/000068549
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Myeloperoxidase (MPO), eosinophil peroxidase (EPX) and lactoperoxidase (LPO) are mammalian peroxidase enzymes possessing similar structures and functions. Here, we demonstrate that the genes encoding these molecules form a cluster on mouse chromosome 11, Genomic sequence analysis revealed that the mouse Lpo gene has similar genomic organization to the corresponding human gene. Our data strongly suggest the evolutionary conservation of mammalian peroxidase genes. Copyright (C) 2002 S. Karger AG, Basel.
引用
收藏
页码：93 / 95
页数：3
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