Casbane Diterpenes from Red Sea Coral Sinularia polydactyla

被引：26
|
作者：
Hegazy, Mohamed-Elamir F. [1 ]
Mohamed, Tarik A. [1 ]
Elshamy, Abdelsamed I. [2 ]
Al-Hammady, Montaser A. [3 ]
Ohta, Shinji [4 ]
Pare, Paul W. [5 ]
机构：
[1] Natl Res Ctr, Dept Phytochem, El Tahrir St, Giza 12622, Egypt
[2] Natl Res, Dept Nat Compound Chem, El Tahrir St, Giza 12622, Egypt
[3] Natl Inst Oceanog & Fisheries, Red Sea Branch, Hurghada 84511, Egypt
[4] Hiroshima Univ, Grad Sch Biosphere Sci, 1-7-1 Kagamiyama, Higashihiroshima 7398521, Japan
[5] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA
来源：
MOLECULES | 2016年 / 21卷 / 03期
关键词：
soft coral; alcyoniidae; Sinularia polydactyla; diterpenes; SOFT CORAL; CEMBRANOIDS; INELEGANS;
D O I：
10.3390/molecules21030308
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4-5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis.
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页数：8
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