Diet as Regulator of Gut Microbiota and its Role in Health and Disease

被引：57

作者：

Sanchez-Tapia, Monica ^{[1
]}

Tovar, Armando R. ^{[1
]}

Torres, Nimbe ^{[1
]}

机构：

[1] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Fisiol Nutr, Av Vasco Quiroga 15, Ciudad De Mexico 14080, Mexico

来源：

ARCHIVES OF MEDICAL RESEARCH | 2019年 / 50卷 / 05期

关键词：

Gut microbiota; Diet; Obesity; Nutrients; Type; 2; diabetes; INDUCED OBESITY; RESISTANT STARCH; INSULIN-RESISTANCE; INFLAMMATION; ENDOTOXEMIA; MODULATION; MECHANISM; MICROFLORA; DIVERSITY; CAPACITY;

D O I：

10.1016/j.arcmed.2019.09.004

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

In recent years, the gut microbiota has been of great interest due to its role in maintaining health and its association with the development of different diseases such as obesity and diabetes. The objective of the present review is to show the main functions of the gut microbiota, the role in the degradation of complex carbohydrates particularly soluble fiber, resistant starches and bioactive compounds particularly polyphenols. In addition, the review will focus on the nutrient-gut microbiota interaction and its role on the development of dysbiosis (imbalance) and low-grade inflammation during the obesity and type 2 diabetes. Finally, several strategies using prebiotics will be discussed to reduce the gut microbiota dysbiosis, and to improve some biochemical abnormalities during obesity and type 2 diabetes. (C) 2019 IMSS. Published by Elsevier Inc.

引用

页码：259 / 268

页数：10

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