Small Silencing RNAs: Piecing Together a Viral Genome

被引：10
|
作者：
van Mierlo, Joel T. [1 ]
van Cleef, Koen W. R. [1 ]
van Rij, Ronald P. [1 ]
机构：
[1] Radboud Univ Nijmegen, Nijmegen Ctr Mol Life Sci, Dept Med Microbiol, Med Ctr,Nijmegen Inst Infect Inflammat & Immun, NL-6500 HB Nijmegen, Netherlands
来源：
CELL HOST & MICROBE | 2010年 / 7卷 / 02期
关键词：
DROSOPHILA; DISCOVERY; VIRUSES;
D O I：
10.1016/j.chom.2010.02.001
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Virus-derived small interfering RNAs (siRNAs) are the hallmark of RNAi-based antiviral immunity. Wu and colleagues demonstrate how viral genomes can be assembled from these small RNA sequences. Their results provide an approach for virus discovery as well as important insights into how these siRNAs mediate antiviral defense.
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页码：87 / 89
页数：3
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