Ammonium and phosphate limitation in 1,3-propanediol production by Klebsiella pneumoniae

被引：10
|
作者：
Zheng, Zong-Ming [1 ]
Xu, Yun-Zhen [2 ]
Wang, Ti-Peng [1 ]
Dong, Chang-Qing [1 ]
Yang, Yong-Ping [1 ]
Liu, De-Hua [2 ]
机构：
[1] N China Elect Univ, Sch Renewable Energy, Natl Engn Lab Power Generat Equipment, Beijing 102206, Peoples R China
[2] Tsinghua Univ, Dept Chem Engn, Beijing 100084, Peoples R China
来源：
BIOTECHNOLOGY LETTERS | 2010年 / 32卷 / 02期
关键词：
Ammonium limitation; Fermentation; Klebsiella pneumoniae; Phosphate limitation; 1,3-Propanediol; MICROBIAL-GROWTH; FERMENTATION; GLYCEROL; SUBSTRATE; CULTURE; PATHWAY;
D O I：
10.1007/s10529-009-0150-y
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Excretion of 1,3-propanediol (1,3-PD) by K. pneumoniae was compared in ammonium- and phosphate-limited chemostat cultures running with an excess of glycerol. 59 and 43% catabolic flux were directed to 1,3-PD in ammonia-limited cultures and phosphate-limited cultures at dilution rate of 0.1 h(-1), respectively. Ammonia-limited fed-batch cultures produced 61 g 1,3-PD l(-1) and a total of 15 g l(-1) organic acid in 36 h. However, phosphate-limited fed-batch cultures excreted 61 g lactate l(-1) and 44 g 1,3-PD l(-1).
引用
收藏
页码：289 / 294
页数：6
相关论文
共 50 条
  • [31] Effects of gltA and arcA Mutations on Biomass and 1,3-Propanediol Production in Klebsiella pneumoniae
    Jung Hun Lee
    Hwi-Min Jung
    Moo-Young Jung
    Min-Kyu Oh
    Biotechnology and Bioprocess Engineering, 2019, 24 : 95 - 102
  • [32] Effects of aldehyde dehydrogenase gene knockout on 1,3-propanediol production by Klebsiella pneumoniae
    Institute of Biochemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China
    不详
    Huagong Xuebao, 2006, 11 (2686-2692):
  • [33] Deletion of poxB, pta, and ackA improves 1,3-propanediol production by Klebsiella pneumoniae
    Jie Lin
    Yongqiang Zhang
    Danfeng Xu
    Gang Xiang
    Zongxiao Jia
    Shuilin Fu
    Heng Gong
    Applied Microbiology and Biotechnology, 2016, 100 : 2775 - 2784
  • [34] PRODUCTION OF 1,3-PROPANEDIOL FROM GLYCEROL BY NEWLY ISOLATED STRAINS OF KLEBSIELLA PNEUMONIAE
    Petrova, Penka
    Petrov, Kaloyan
    Beschkov, Venko
    COMPTES RENDUS DE L ACADEMIE BULGARE DES SCIENCES, 2009, 62 (02): : 233 - 242
  • [35] Deletion of ldhA and aldH genes in Klebsiella pneumoniae to enhance 1,3-propanediol production
    Chen, Lifei
    Ma, Chunling
    Wang, Ruiming
    Yang, Jianlou
    Zheng, Haijie
    BIOTECHNOLOGY LETTERS, 2016, 38 (10) : 1769 - 1774
  • [36] Production of 1,3-propanediol in Klebsiella pneumoniae induced by dielectric barrier discharge plasma
    Dong, Xiaoyu
    Xiu, Zhilong
    Hou, Yingmin
    Li, Shuang
    Zhang, Daijia
    Ren, Chunsheng
    JOURNAL OF BIOTECHNOLOGY, 2008, 136 : S327 - S327
  • [37] Changes in the Activities of Metabolic Enzymes in Klebsiella pneumoniae during 1,3-Propanediol Production
    Wang, Ya-Jun
    Zhao, Li
    Xu, Jia-Jie
    Fu, Shui-Lin
    Gong, Heng
    Huadong Ligong Daxue Xuebao /Journal of East China University of Science and Technology, 2007, 33 (04): : 481 - 484
  • [38] Influences of 3-hydroxypropionaldehyde and lactate on the production of 1,3-propanediol by Klebsiella pneumoniae
    Zhong Z.
    Liu L.
    Zhou J.
    Gao L.
    Xu J.
    Fu S.
    Gong H.
    Bioresources and Bioprocessing, 1 (1)
  • [39] Deletion of poxB, pta, and ackA improves 1,3-propanediol production by Klebsiella pneumoniae
    Lin, Jie
    Zhang, Yongqiang
    Xu, Danfeng
    Xiang, Gang
    Jia, Zongxiao
    Fu, Shuilin
    Gong, Heng
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016, 100 (06) : 2775 - 2784
  • [40] Effects of gltA and arcA Mutations on Biomass and 1,3-Propanediol Production in Klebsiella pneumoniae
    Lee, Jung Hun
    Jung, Hwi-Min
    Jung, Moo-Young
    Oh, Min-Kyu
    BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, 2019, 24 (01) : 95 - 102
12345