Advances in measuring lifespan in the yeast Saccharomyces cerevisiae

被引：66

作者：

Minois, N ^{[1
]}

Frajnt, M ^{[1
]}

Wilson, C ^{[1
]}

Vaupel, JW ^{[1
]}

机构：

[1] Max Planck Inst Demog Res, D-18057 Rostock, Germany

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2005年 / 102卷 / 02期

关键词：

biodemography;

D O I：

10.1073/pnas.0408332102

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Much research aimed at discovering the genetic bases of longevity focuses on the budding yeast Saccharomyces cerevisiae. Unfortunately, yeast researchers use a definition of longevity not applied to other species. We propose here a method that makes it possible to estimate for yeast the same measures of longevity calculated for other species. We also show that the conventional method (equating longevity with the number of offspring) is only an approximate measure of true chronological lifespan. Our method will allow results for yeast to be compared more correctly with those for other species.

引用

页码：402 / 406

页数：5

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