The potential of novel ribonucleotide reductase inhibitors, Didox and Trimidox, compared to hydroxyurea to enhance NRTI antiviral activity in vivo

被引:0
|
作者
Sumpter, R
Elford, H
Inayat, M
Sugg, T
Tsai, P
Gallicchio, V
机构
[1] Mol Hlth Inc, Richmond, VA USA
[2] Univ Kentucky, Lexington, KY USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
26
引用
收藏
页码:A48 / A48
页数:1
相关论文
共 45 条
  • [41] Effects of some novel inhibitors of C17,20-lyase and 5α-reductase in vitro and in vivo and their potential role in the treatment of prostate cancer
    Nnane, IP
    Kato, K
    Liu, Y
    Lu, Q
    Wang, X
    Ling, YZ
    Brodie, A
    CANCER RESEARCH, 1998, 58 (17) : 3826 - 3832
  • [42] In vivo antiviral activity of novel human immunodeficiency virus type 1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model
    Schito, ML
    Goel, A
    Song, Y
    Inman, JK
    Fattah, RJ
    Rice, WG
    Turpin, JA
    Sher, A
    Appella, E
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2003, 19 (02) : 91 - 101
  • [43] Inhibitors of bacterial enoyl-ACP reductase (FABI) 1: Discovery of a novel aminopyridine-based FABI inhibitor with in vivo antibacterial activity.
    Miller, WH
    Seefeld, MA
    Newlander, KA
    Uzinskas, IN
    Burgess, WJ
    Manley, PJ
    Heerding, DA
    Takata, DT
    Yuan, CCK
    Head, MS
    Berry, V
    Greenwood, R
    Jaworski, DD
    Jepras, RI
    Moore, TT
    Payne, DJ
    Pearson, SC
    Rittenhouse, SF
    Slater-Radosti, CE
    Straub, RJ
    Wallis, NG
    DeWolf, WE
    Keller, PM
    Jansen, CA
    Qiu, XY
    Chen, E
    Salyers, KL
    Vaidya, K
    Fosberry, AP
    Smyth, MG
    Huffman, WF
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 222 : U670 - U671
  • [44] Chemical synthesis, biological evaluation and structure-activity relationship analysis of azaisoindolinones, a novel class of direct enoyl-ACP reductase inhibitors as potential antimycobacterial agents
    Deraeve, Celine
    Dorobantu, Ioana Miruna
    Rebbah, Farah
    Le Quemener, Frederic
    Constant, Patricia
    Quemard, Annaik
    Bernardes-Genisson, Vania
    Bernadou, Jean
    Pratviel, Genevieve
    BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (21) : 6225 - 6232
  • [45] Design, synthesis, in vitro and in vivo evaluation of novel pyrrolizine-based compounds with potential activity as cholinesterase inhibitors and anti-Alzheimer's agents
    El-Sayed, Nehad Abou-Elmagd
    Farag, Awatef El-Said
    Ezzat, Manal Abdel Fattah
    Akincioglu, Hulya
    Gulcin, Ilhami
    Abou-Seri, Sahar Mahmoud
    BIOORGANIC CHEMISTRY, 2019, 93