The potential of novel ribonucleotide reductase inhibitors, Didox and Trimidox, compared to hydroxyurea to enhance NRTI antiviral activity in vivo

被引：0
|
作者：
Sumpter, R
Elford, H
Inayat, M
Sugg, T
Tsai, P
Gallicchio, V
机构：
[1] Mol Hlth Inc, Richmond, VA USA
[2] Univ Kentucky, Lexington, KY USA
来源：
ANTIVIRAL RESEARCH | 2003年 / 57卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
26
引用
收藏
页码：A48 / A48
页数：1
相关论文
共 45 条
  • [1] The potential of novel ribonucleotide reductase inhibitors, Didox and Trimidox, compared to hydroxyurea to enhance abacavir antiviral activity in vivo.
    Elford, H
    Sumpter, R
    Inayat, M
    Gallicchio, V
    ANTIVIRAL RESEARCH, 2002, 53 (03) : A46 - A46
  • [2] The potential of novel ribonucleotide reductase inhibitors, Didox and Trimidox, to reduce doxorubicin cardiotoxicity and enhance antitumor activity.
    Elford, HL
    Cardounel, AJ
    Mikhail, E
    Szekeres, T
    Zweier, JL
    CLINICAL CANCER RESEARCH, 2001, 7 (11) : 3749S - 3749S
  • [3] Hydroxyurea (HU) and the novel ribonucleotide reductase inhibitors (RRI) trimidox (TX) and didox (DX) enhance the anti-viral activity of abacavir (ABC) in-vivo
    Sumpter, R
    Inayat, M
    Mayhew, C
    Yost, E
    Cibull, M
    Elford, H
    Gallicchio, V
    XIV INTERNATIONAL AIDS CONFERENCE: BASIC SCIENCES, 2002, : 211 - 214
  • [4] The in vitro inhibition of cytomegalovirus by novel ribonucleotide reductase inhibitors didox and trimidox
    Inayat, MS
    Gallicchio, VS
    Garvy, BA
    Elford, HL
    Oakley, OR
    ANTIVIRAL RESEARCH, 2005, 65 (03) : A74 - A75
  • [5] Ribonucleotide reductase inhibitors didox and trimidox compared to hydroxyurea to inhibit retrovirus replication alone or in combination with abacavir, ddl or tenofovir
    Sumpter, R
    Mayhew, C
    Inayat, M
    Sugg, T
    Tsai, P
    Elford, H
    Gallicchio, V
    ANTIVIRAL RESEARCH, 2004, 62 (02) : A29 - A29
  • [6] In vivo and in vitro comparison of the short-term hematopoietic toxicity between hydroxyurea and trimidox or didox, novel ribonucleotide reductase inhibitors with potential anti-HIV-1 activity
    Mayhew, CN
    Phillips, JD
    Greenberg, RN
    Birch, NJ
    Elford, HL
    Gallicchio, VS
    STEM CELLS, 1999, 17 (06) : 345 - 356
  • [7] Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir
    Bhave, Sukhada
    Elford, Howard
    McVoy, Michael A.
    ANTIVIRAL RESEARCH, 2013, 100 (01) : 151 - 158
  • [8] The virtues of unique ribonucleotide reductase inhibitors didox and trimidox for retrovirus therapy
    Elford, Howard
    Lee, Ron
    Turchan, Jadwiga
    Gallicchio, Vincent
    Ussery, Michael
    Hiscott, John
    Nath, Avindra
    ANTIVIRAL RESEARCH, 2007, 74 (03) : A65 - A66
  • [9] Inhibition of allogeneic inflammatory responses by the Ribonucleotide Reductase Inhibitors, Didox and Trimidox
    Inayat, Mohammed S.
    El-Amouri, Ismail S.
    Bani-Ahmad, Mohammad
    Elford, Howard L.
    Gallicchio, Vincent S.
    Oakley, Oliver R.
    JOURNAL OF INFLAMMATION-LONDON, 2010, 7
  • [10] Inhibition of allogeneic inflammatory responses by the Ribonucleotide Reductase Inhibitors, Didox and Trimidox
    Mohammed S Inayat
    Ismail S El-Amouri
    Mohammad Bani-Ahmad
    Howard L Elford
    Vincent S Gallicchio
    Oliver R Oakley
    Journal of Inflammation, 7
12345