Risk factors for kidney damage in COVID-19 patients admitted to the intensive care unit

被引:1
|
作者
Sarkisian, Diana K. [1 ]
Chebotareva, Natalia, V [3 ]
McDonnell, Valerie [3 ]
Oganesyan, Armen, V [4 ]
Krasnova, Tatyana N. [1 ]
Makarov, Egor A. [2 ]
机构
[1] Lomonosov Moscow State Univ, Fac Med, Dept Internal Med, Moscow, Russia
[2] Lomonosov Moscow State Univ, Fac Med, Moscow, Russia
[3] Sechenov First Moscow State Med Univ, Nephol Dept, Moscow, Russia
[4] ZAO Grp Co Medsi Clin Hosp 1, Intens Care Unit, Moscow, Russia
关键词
COVID-19; proteinuria; tubular dysfunction; acute kidney injury; CLINICAL CHARACTERISTICS; HOSPITALIZED-PATIENTS; WUHAN; VALIDATION;
D O I
10.15275/rusomj.2021.0203
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background - Acute kidney injury (AKI) reaches 29% in the intensive care unit (ICU). Our study aimed to determine the prevalence, features, and the main AKI factors in critically ill patients with coronavirus disease 2019 (COVID-19). Material and Methods - The study included 37 patients with COVID-19. We analyzed the total blood count test results, biochemical profile panel, coagulation tests, and urine samples. We finally estimated the markers of kidney damage and mortality. Result - All patients in ICU had proteinuria, and 80.5% of patients had hematuria. AKI was observed in 45.9% of patients. Independent risk factors were age more than 60 years, increased C-reactive protein (CRP) level, and decreased platelet count. Conclusion - Kidney damage was observed in most critically ill patients with COVID-19. The independent risk factors for AKI in critically ill patients were elderly age, a cytokine response with a high CRP level.
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页数:8
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