Anti-Hu-associated paraneoplastic sensory neuropathy with peripheral nerve demyelination and microvasculitis

被引：25
|
作者：
Eggers, C
Hagel, C
Pfeiffer, G
机构：
[1] Univ Hamburg Hosp, Dept Neurol, D-20246 Hamburg, Germany
[2] Univ Hamburg Hosp, Dept Neuropathol, D-20246 Hamburg, Germany
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 1998年 / 155卷 / 02期
关键词：
sensory neuropathy; paraneoplastic; anti-Hu-antibody; demyelination; vasculitis;
D O I：
10.1016/S0022-510X(97)00304-3
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A patient had a paraneoplastic autonomic, then sensory, then sensory-motor neuropathy with small cell lung carcinoma and a high titer Anti-Hu antibody to nuclei of neuronal cells. As an unusual finding there was electrophysiological and pathological evidence of demyelination and a peripheral nerve microvasculitis. The relationship of microvasculitis and peripheral nerve demyelination is discussed and their occurrence with paraneoplastic anti-Hu-associated sensory neuropathy is suggested not to be by chance. (C) 1998 Elsevier Science B.V.
引用
收藏
页码：178 / 181
页数：4
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