Terpenoids from Salvia trijuga

被引:25
|
作者
Pan, Zheng-Hong [1 ,2 ,3 ]
Wang, Yuan-Yuan [1 ]
Li, Ming-Ming [1 ]
Xu, Gang [1 ]
Peng, Li-Yan [1 ]
He, Juan [1 ]
Zhao, Yu [1 ]
Li, Yan [1 ]
Zhao, Qin-Shi [1 ]
机构
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
[2] Chinese Acad Sci, Guangxi Inst Bot, Guilin 541006, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
来源
JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 06期
基金
中国国家自然科学基金;
关键词
PTEROCARPUS-SANTALINUS; MILTIORRHIZA BUNGE; TRITERPENE; SESQUITERPENES; CONSTITUENTS; ELUCIDATION; DITERPENES; ROOTS;
D O I
10.1021/np100250w
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Nine new germacrane sesquiterpenes, trijugins A-I (1-9), a new lupane triterpenoid, 3 alpha-O-acetyl-20(29)-lupen-2 alpha-ol (10), and 24 known terpenoids were isolated from Salvia trijuga. The structure of compound I was confirmed by single-crystal X-ray diffraction. Compounds 1-10 and 32 were evaluated for their cylotoxicity against live human tumor cell lines. Compounds 9 and 32 exhibited moderate toxicity effects against several cell lines.
引用
收藏
页码:1146 / 1150
页数:5
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