Fungal sinusitis

被引：3

作者：

Lafont, E. ^{[1
]}

Aguilar, C. ^{[1
]}

Vironneau, P. ^{[3
]}

Kania, R. ^{[3
]}

Alanio, A. ^{[2
,4
]}

Poiree, S. ^{[5
]}

Lortholary, O. ^{[1
,2
]}

Lanternier, F. ^{[1
,2
]}

机构：

[1] Univ Paris 05, Hop Necker Enfants Malad, AP HP, Serv Malad Infect & Trop,Inst Imagine, 149,Rue Sevres, F-75743 Paris, France

[2] CNRS, Ctr Natl Reference Mycoses Invas & Antifong, URA3012, Unite Mycol Mol,Inst Pasteur, 25,Rue Docteur Roux, F-75724 Paris, France

[3] Univ Paris Sorbonne Cite 2, Hop Lariboisiere, AP HP, EA REMES Patient Reported Outcomes 7334,Serv ORL, 2,Rue Ambroise Pare, F-75475 Paris, France

[4] Hop St Louis, Lab Parasitol Mycol, 1,Ave Claude Vellefaux, F-75475 Paris, France

[5] Hop Necker Enfants Malad, AP HP, Serv Radiol Adulte, 149,Rue Sevres, F-75743 Paris, France

来源：

REVUE DES MALADIES RESPIRATOIRES | 2017年 / 34卷 / 06期

关键词：

Sinusitis; Fungi; Diagnosis; Treatment; POSITRON-EMISSION-TOMOGRAPHY; POLYMERASE-CHAIN-REACTION; INVASIVE ASPERGILLOSIS; RHINOCEREBRAL ASPERGILLOSIS; DISSEMINATED INFECTION; TRANSPLANT RECIPIENTS; COMBINATION THERAPY; ANTIFUNGAL THERAPY; MURINE MODEL; DIAGNOSIS;

D O I：

10.1016/j.rmr.2016.09.004

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Although sinusitis affects about 20 % of the population, fungal sinusitis is rare. Aspergillus sp. are most frequently implicated. Fungal sinusitis represents a wide spectrum of disorders, including acute or chronic and invasive or non-invasive forms. Invasive fungal sinusitis may develop in an immunocompromised or diabetic patient, whereas non-invasive fungal sinusitis should be considered in a chronic situation, resistant to antibiotics in immunocompetent patients. Allergic fungal sinusitis is related to hypersensitivity of the host to the fungus. The diagnosis of these infections requires radiological examination and endoscopy with mucosal biopsies examined histologically and mycologically in order to distinguish the different types of sinusitis. In the non-invasive forms, surgical treatment is essential, sometimes combined with antifungal and anti-inflammatory treatment. The invasive forms require antifungal treatment, combined with surgery in some forms, particularly mucormycosis. (C) 2017 SPLF. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：672 / 692

页数：21

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