Vaccination using epitopes with higher MHC class I affinity elicits CD8+T cells with increased PD-1 expression

被引:0
|
作者
Zahm, Christopher D. [1 ]
McNeel, Douglas [1 ]
机构
[1] Univ Wisconsin, Madison, WI USA
关键词
D O I
10.1158/1538-7445.AM2015-2501
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2501
引用
收藏
页数:1
相关论文
共 50 条
  • [31] PD-1/PD-L1 Blockade Therapy for Tumors with Downregulated MHC Class I Expression
    Smahel, Michal
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (06)
  • [32] Exhaustion of intra-hepatic CD8+T cells targeting intact and escaped MHC class I epitopes in chronic phase of hepatitis C virus infection
    Callendret, Benoit
    Bowen, David
    Fuller, Michael
    Eccleston, Heather
    Rutckiewitz, Jennifer
    Hasselschwert, Dana
    Freeman, Gordon
    Walker, Christopher
    JOURNAL OF IMMUNOLOGY, 2010, 184
  • [33] Infiltration of CD8 T Cells and Expression of PD-1 and PD-L1 in Synovial Sarcoma
    Nowicki, Theodore S.
    Akiyama, Ryan
    Huang, Rong Rong
    Shintaku, I. Peter
    Wang, Xiaoyan
    Tumeh, Paul C.
    Singh, Arun
    Chmielowski, Bartosz
    Denny, Christopher
    Federman, Noah
    Ribas, Antoni
    CANCER IMMUNOLOGY RESEARCH, 2017, 5 (02) : 118 - 126
  • [34] Increased expression of PD-1 in CD8 + CD3 + T cells correlates with EBV viral load in MS patients
    Najmadini, Atefeh
    Mohammadi, Mohammad Mahdi
    Langroudi, Ladan
    Meimand, Hosseinali Ebrahimi
    Mahmoodi, Merat
    Mirzaei, Moghadameh
    JOURNAL OF NEUROVIROLOGY, 2022, 28 (4-6) : 497 - 504
  • [35] Increased expression of PD-1 in CD8 + CD3 + T cells correlates with EBV viral load in MS patients
    Atefeh Najmadini
    Mohammad Mahdi Mohammadi
    Ladan Langroudi
    Hosseinali Ebrahimi Meimand
    Merat Mahmoodi
    Moghadameh Mirzaei
    Journal of NeuroVirology, 2022, 28 : 497 - 504
  • [36] Functional avidity maturation of CD8+T cells without selection of higher affinity TCR
    Slifka, MK
    Whitton, JL
    NATURE IMMUNOLOGY, 2001, 2 (08) : 711 - 717
  • [37] Dynamic quantification of MHC class I-peptide presentation to CD8+T cells via intracellular cytokine staining
    Pang, Ken C.
    Wei, Joe Q. Z.
    Chen, Weisan
    JOURNAL OF IMMUNOLOGICAL METHODS, 2006, 311 (1-2) : 12 - 18
  • [38] Selective deletion of HY-reactive CD8+T cells by saporin-coupled MHC class I tetramers
    Hess, Paul R.
    Murray, Sabrina L.
    Buntzman, Adam S.
    Young, Ellen F.
    Steele, Shaun P.
    Collins, Edward J.
    Frelinger, Jeffrey A.
    JOURNAL OF IMMUNOLOGY, 2009, 182
  • [39] The assessment of antigen-specific CD8+T cells through the combination of MHC class I tetramer and intracellular staining
    Appay, V
    Rowland-Jones, SL
    JOURNAL OF IMMUNOLOGICAL METHODS, 2002, 268 (01) : 9 - 19
  • [40] Relapse after allo-SCT is associated with high PD-1 and TIGIT expression on tumor-reactive CD8+T cells
    Hutten, T.
    Norde, W.
    Woestenenk, R.
    Maas, F.
    Kester, M.
    Falkenburg, F.
    Schaap, N.
    Jansen, J.
    Dolstra, H.
    Hobo, W.
    BONE MARROW TRANSPLANTATION, 2017, 52 : S162 - S162