From lifetime to evolution: escales of human gut microbiota adaptation

被引：76

作者：

Quercia, Sara ^{[1
]}

Candela, Marco ^{[1
]}

Giuliani, Cristina ^{[2
,3
]}

Turroni, Silvia ^{[1
]}

Luiselli, Donata ^{[2
,3
]}

Rampelli, Simone ^{[1
]}

Brigidi, Patrizia ^{[1
]}

Franceschi, Claudio ^{[4
,5
,6
,7
,8
]}

Bacalini, Maria Giulia ^{[4
,5
]}

Garagnani, Paolo ^{[4
,5
,9
]}

Pirazzini, Chiara ^{[4
,5
]}

机构：

[1] Univ Bologna, Dept Pharm & Biotechnol, I-40126 Bologna, Italy

[2] Univ Bologna, Lab Mol Anthropol, Dept Biol Geol & Environm Sci, BiGEA, I-40126 Bologna, Italy

[3] Univ Bologna, Ctr Genome Biol, I-40126 Bologna, Italy

[4] Univ Bologna, Dept Expt Diagnost & Specialty Med, DIMES, I-40126 Bologna, Italy

[5] Univ Bologna, Interdept Ctr L Galvani CIG, CIG, I-40126 Bologna, Italy

[6] IRCSS, Inst Neurol Sci Bologna, Bologna, Italy

[7] IGM CNR, Inst Mol Genet, Unit Bologna IOR, Bologna, Italy

[8] CNR, Inst Organ Synth & Photoreact ISOF, I-40126 Bologna, Italy

[9] St Orsola Malpighi Univ Hosp, Ctr Appl Biomed Res, CRBA, Bologna, Italy

来源：

FRONTIERS IN MICROBIOLOGY | 2014年 / 5卷

关键词：

gut microbiota; aging; environmental stimuli; co-evolution; biological adaptation; INTESTINAL MICROBIOTA; FECAL MICROFLORA; HOST GENETICS; TEMPORAL STABILITY; BODY HABITATS; DIET; BACTERIAL; METABOLITES; DISEASE; SHAPES;

D O I：

10.3389/fmicb.2014.00587

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human beings harbor gut microbial communities that are essential to preserve human health. Molded by the human genome, the gut microbiota (GM) is an adaptive component of the human superorganisms that allows host adaptation at different timescales, optimizing host physiology from daily life to lifespan scales and human evolutionary history. The GM continuously changes from birth up to the most extreme limits of human life, reconfiguring its metagenomic layout in response to daily variations in diet or specific host physiological and immunological needs at different ages. On the other hand, the microbiota plasticity was strategic to face changes in lifestyle and dietary habits along the course of the recent evolutionary history, that has driven the passage from Paleolithic hunter-gathering societies to Neolithic agricultural farmers to modern Westernized societies.

引用

页数：9

共 50 条

[21] Adaptation of the Human Gut Microbiota Metabolic Network During the First Year After Birth
Fuertes, Alvaro
Perez-Burillo, Sergio
Apaolaza, Inigo
Valles, Yvonne
Pilar Francino, M.
Angel Rufian-Henares, Jose
Planes, Francisco J.
FRONTIERS IN MICROBIOLOGY, 2019, 10
[22] Adaptation of human gut microbiota to bariatric surgeries in morbidly obese patients: A systematic review
Ejtahed, Hanieh-Sadat
Angoorani, Pooneh
Hasani-Ranjbar, Shirin
Siadat, Seyed-Davar
Ghasemi, Nasrin
Larijani, Bagher
Soroush, Ahmad-Reza
MICROBIAL PATHOGENESIS, 2018, 116 : 13 - 21
[23] Introduction to the human gut microbiota
Thursby, Elizabeth
Juge, Nathalie
BIOCHEMICAL JOURNAL, 2017, 474 (11) : 1823 - 1836
[24] Describing human gut microbiota
Lei Tang
Nature Methods, 2019, 16 : 805 - 805
[25] Carbohydrates and the human gut microbiota
Chassard, Christophe
Lacroix, Christophe
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2013, 16 (04): : 453 - 460
[26] Gut microbiota and human health
Masson, Elsevier
ACTUALITES PHARMACEUTIQUES, 2022, 61 (616): : 7 - 7
[27] The Human Gut Microbiota and Undernutrition
Gordon, Jeffrey I.
Dewey, Kathryn G.
Mills, David A.
Medzhitov, Ruslan M.
SCIENCE TRANSLATIONAL MEDICINE, 2012, 4 (137)
[28] Describing human gut microbiota
Tang, Lei
NATURE METHODS, 2019, 16 (09) : 805 - 805
[29] The "extra'' human metabolic organ: possible contributions of the gut microbiota to hominin evolution
Coppeto, D. J.
AMERICAN JOURNAL OF HUMAN BIOLOGY, 2013, 25 (02) : 254 - 254
[30] Adaptation of the Gut Microbiota of Amur Tigers to a Special Diet
Yuhang Zhu
Zhiqiang Han
Haijun Wang
Cunfa Liu
Huazhe Si
Chao Xu
Current Microbiology, 2021, 78 : 1628 - 1635

← 1 2 3 4 5 →