A two-step synthesis of 11-substituted 6-amino-benzo[c]phenanthridin derivatives, a new class of antitumor agents

被引：0

|

作者：

Kock, I ^{[1
]}

Heber, D ^{[1
]}

Weide, M ^{[1
]}

Wolschendorf, U ^{[1
]}

Clement, B ^{[1
]}

机构：

[1] Univ Kiel, B Clement Pharmaceut Inst, D-24118 Kiel, Germany

来源：

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2004年 / 23卷

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D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

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页码：S36 / S36

页数：1

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[31] Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents.: Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-β-D-glucopyranosyl]-5H,13H-benzo[b]thienyl[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model.(vol 47, pg 1609, 2004)
Balasubramanian, BN
Laurent, DRS
Saulnier, MG
Long, BH
Bachand, C
Beaulieu, F
Clarke, W
Deshpande, M
Eummer, J
Fairchild, CR
Frennesson, DB
Kramer, R
Lee, FY
Mahler, M
Martel, A
Naidu, BN
Rose, WC
Russell, J
Ruediger, E
Solomon, C
Stoffan, KM
Wong, H
Wright, JJ
Zimmermann, K
Vyas, DM
JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (02) : 654 - 654

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