A single dose of the GalNAc-siRNA, AB-729, results in prolonged reductions in HBsAg, HBcrAg, HBV DNA and HBV RNA in the absence of nucleos (t)ide analogue therapy in HBeAg negative subjects with chronic hepatitis B infection

被引:0
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作者
Gane, Edward [1 ]
Sevinsky, Heather [2 ]
Yuen, Man-Fung [3 ]
Anderson, Mark [4 ]
Cloherty, Gavin [4 ]
Thi, Emily P. [2 ]
Wattamwar, Tosh [2 ]
Sofia, Michael J. [2 ]
Gray, Kevin [2 ]
Antoniello, Deana [2 ]
Eley, Timothy [2 ]
Picchio, Gaston [2 ]
Sims, Karen [2 ]
机构
[1] Univ Auckland, Auckland, New Zealand
[2] Arbutus Biopharma, Warminster, PA USA
[3] Queen Mary Hosp, Hong Kong, Peoples R China
[4] Abbott Labs, Abbott Pk, IL 60064 USA
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中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
PO-2879
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页码:S762 / S763
页数:2
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