Effect of prenatal and early postnatal environmental influences on the brain and psyche

The psyche of a human being is formed in strict correlation with the development of the brain. Genetic, epigenetic regulatory and prenatal influences through the brain of the mother as well as postnatal influences, predominantly as early childhood attachment experiences are all intertwined with each other. This takes place at three "limbic levels": a lower level at which the infantile temperament resides, a middle level of early childhood impressioning experiences and an upper limbic level of socialization. The cognitive language level develops in a relatively independent manner. At the three limbic levels six psychoneural systems are operative, namely the stress processing, the self-calming, the impulse inhibiting, the motivation, the attachment and the reality and risk perception systems. Mental disorders are characterized throughout by disorders of the first two systems, predominantly in the form of greatly increased cortisol levels and greatly reduced serotinin levels. These then induce deficits in other systems; however, in less severe cases compensatory processes can occur via an attachment-related increased release of oxytocin. Similar processes also occur within the "therapeutic alliance" in the patient-therapist relationship.