The descriptive epidemiology of rheumatoid arthritis in Catalonia: a retrospective study using routinely collected data

被引:16
|
作者
Fina-Aviles, F. [1 ]
Medina-Peralta, M. [1 ]
Mendez-Boo, L. [1 ]
Hermosilla, E. [2 ]
Elorza, J. M. [2 ]
Garcia-Gil, M. [1 ,2 ]
Ramos, R. [1 ,2 ]
Bolibar, B. [2 ]
Javaid, M. K. [3 ,4 ]
Edwards, C. J. [5 ]
Cooper, C. [3 ,4 ]
Arden, N. K. [3 ,4 ]
Prieto-Alhambra, D. [2 ,3 ,4 ,6 ]
机构
[1] Inst Catala Salut, Primary Care Dept, Av Gran Via Corts Catalanes 587,3rd Floor, Barcelona 08007, Spain
[2] Univ Autonoma Barcelona, IDIAP Jordi Gol Primary Care Res Inst, Av Gran Via Corts Catalanes 587, Barcelona 08007, Spain
[3] Univ Oxford, Oxford NIHR Musculoskeletal Biomed Res Unit, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Windmill Rd, Oxford OX3 7LD, England
[4] Univ Southampton, MRC, Lifecourse Epidemiol Unit, Tremona Rd, Southampton SO16 6YD, Hants, England
[5] Southampton Gen Hosp, Tremona Rd, Southampton SO16 6YD, Hants, England
[6] IDIAP Jordi Gol, SIDIAP Database, Av Gran Via Corts Catalanes 587, Barcelona 08007, Spain
关键词
Arthritis; Electronic health records; Epidemiology; Incidence; Prevalence; Rheumatoid; POPULATION-BASED COHORT; PREVALENCE; DISEASES; CRITERIA; FRACTURE; MORTALITY; BURDEN; FRANCE; GREECE; SPAIN;
D O I
10.1007/s10067-014-2801-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Information on the epidemiology of rheumatoid arthritis (RA) in Southern Europe is scarce. We estimated the age- and gender-adjusted incidence and prevalence of RA in Catalonia using routinely collected primary care records. We identified incident (2009-2012) and prevalent (on 31 December 2012) cases of RA in the SIDIAP database using ICD-10 codes. SIDIAP contains anonymized data from computerized primary care records for about five million adults (> 80 % of the population). We estimated age- (5-year groups) and gender-specific, and directly standardized incidence and prevalence of RA and confidence intervals (95% CIs) assuming a Poisson distribution. A total of 20,091 prevalent (among whom 5,796 incident) cases of RA were identified among 4,796,498 study participants observed for up to 4 years. Rates of RA increased with age in both genders, peaking at the age of 65-70 years. Age- and gender-standardized incidence and prevalence rates were 0.20/1,000 person-years (95% CI 0.19-0.20) and 4.17/1,000 (4.11-4.23) respectively. Rheumatoid factor was positive (a parts per thousand yen10 IU/mL) in 1,833 (73.9 %) of 2,482 cases tested in primary care. The incidence and prevalence of RA in Catalonia are similar to those of other Southern European regions, and lower than those of northern areas. This data will inform health care planning and resource allocation.
引用
收藏
页码:751 / 757
页数:7
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