(1S, 2R, 2′S, 3′aS,5R)-2′-[(1R)-1-hydroxyethyl]-2-isopropyl-5,5′-dimethyl-3′,3′a-dihydro-2′H-spiro[cyclohexane-1,6′-imidazo[1,5-b]isoxazol]4′(5′H)-one

被引：0

作者：

Aouadi, Kaiss

Jeanneau, Erwann

Praly, Jean-Pierre

机构：

[1] Univ Lyon 1, Ctr Diffractometrie Henri Longchambon, F-69622 Villeurbanne, France

[2] Univ Lyon 1, CPE Lyon, Lab Chim Organ 2, UMR 5181,CNRS, F-69622 Villeurbanne, France

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2007年 / 63卷

关键词：

D O I：

10.1107/S1600536807006824

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

Cycloaddition of a (-)-menthone-derived nitrone to racemic but-3-en-2-ol led to two spirobicyclic heterocycles, with opposite configurations at the C atom attached to the OH group. This paper describes the S epimer of the 1-hydroxyethyl substituent in imidazoisoxazole C17H30N2O3, (I). The R epimer, (II), is presented in the previous article [Aouadi, Jeanneau & Praly (2007), Acta Cryst. E67, o1324 - o1326]. The absolute configurations of both epimers were assigned from the known configuration of the starting (-)-menthone derived nitrone. In (I), there is an O- H (. . .) O hydrogen bond (O-H O-. . . = 1.96 angstrom and O - H (. . .) O = 165 degrees) that concatenates the molecules along the b axis. In addition, there are C-H (. . .) O and C-H (. . .) N hydrogen bonds.

引用

页码：o1327 / o1329

页数：3

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