Molecular Insights into Compound-Transporter Interactions: The Case of Inhibitors of Gram-Negative Bacteria Efflux Pumps

被引：0
|
作者：
Sjuts, Hanno [1 ]
Vargiu, Attilio V. [2 ]
Kwasny, Steven M. [3 ]
Nguyen, Son T. [3 ]
Kim, Hong-Suk [4 ]
Ding, Xiaoyuan [3 ]
Ornik, Alina R. [1 ]
Ruggerone, Paolo [2 ]
Bowlin, Terry L. [5 ]
Nikaido, Hiroshi [6 ]
Pos, Klaas M. [1 ]
Opperman, Timothy J. [3 ]
机构：
[1] Goethe Univ, Inst Biochem, Frankfurt, Germany
[2] Univ Cagliari, Phys, Monserrato, CA, Italy
[3] Microbiotix Inc, Dept Mol & Cellular Biol, Worcester, MA USA
[4] Univ Calif Berkeley, Berkeley, CA 94720 USA
[5] Microbiotix Inc, Inst Biochem, Worcester, MA USA
[6] Univ Calif Berkeley, Phys, Berkeley, CA 94720 USA
来源：
BIOPHYSICAL JOURNAL | 2017年 / 112卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2016.11.1483
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
1340-Pos
引用
收藏
页码：274A / 274A
页数：1
相关论文
共 50 条
  • [1] Inhibitors of efflux pumps in Gram-negative bacteria
    Pagès, JM
    Masi, M
    Barbe, J
    TRENDS IN MOLECULAR MEDICINE, 2005, 11 (08) : 382 - 389
  • [2] Multidrug efflux pumps of gram-negative bacteria
    Nikaido, H
    JOURNAL OF BACTERIOLOGY, 1996, 178 (20) : 5853 - 5859
  • [3] New Multidrug Efflux Inhibitors for Gram-Negative Bacteria
    Marshall, Robert L.
    Lloyd, Georgina S.
    Lawler, Amelia J.
    Element, Sarah J.
    Kaur, Jaswant
    Ciusa, Maria Laura
    Ricci, Vito
    Tschumi, Andreas
    Kuhne, Holger
    Alderwick, Luke J.
    Piddock, Laura J., V
    MBIO, 2020, 11 (04): : 1 - 19
  • [4] Antibiotic efflux pumps in Gram-negative bacteria:: the inhibitor response strategy
    Mahamoud, Abdallah
    Chevalier, Jacqueline
    Alibert-Franco, Sandrine
    Kern, Winfried V.
    Pages, Jean-Marie
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 59 (06) : 1223 - 1229
  • [5] Efflux Pumps of Gram-Negative Bacteria, a New Target for New Molecules
    Pages, Jean-Marie
    Alibert-Franco, Sandrine
    Mahamoud, Abdallah
    Bolla, Jean-Michel
    Davin-Regli, Anne
    Chevalier, Jacqueline
    Garnotel, Eric
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2010, 10 (18) : 1848 - 1857
  • [6] Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance
    Blair, Jessica M. A.
    Richmond, Grace E.
    Piddock, Laura J. V.
    FUTURE MICROBIOLOGY, 2014, 9 (10) : 1165 - 1177
  • [7] Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update
    Blair, Jessica M. A.
    Piddock, Laura J. V.
    CURRENT OPINION IN MICROBIOLOGY, 2009, 12 (05) : 512 - 519
  • [8] RND-type drug efflux pumps from Gram-negative bacteria: molecular mechanism and inhibition
    Venter, Henrietta
    Mowla, Rumana
    Ohene-Agyei, Thelma
    Ma, Shutao
    FRONTIERS IN MICROBIOLOGY, 2015, 6
  • [9] Extending the Potency and Lifespan of Antibiotics: Inhibitors of Gram-Negative Bacterial Efflux Pumps
    Duffey, Maelle
    Jumde, Ravindra P.
    da Costa, Renata M. A.
    Ropponen, Henni-Karoliina
    Blasco, Benjamin
    Piddock, Laura J. V.
    ACS INFECTIOUS DISEASES, 2024, 10 (05): : 1458 - 1482
  • [10] Efflux pumps: an answer to Gram-negative bacterial resistance?
    Wiggins, P
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2004, 13 (08) : 899 - 902
12345