Efflux pumps: an answer to Gram-negative bacterial resistance?

被引：8
|
作者：
Wiggins, P [1 ]
机构：
[1] PharmSouth, Dothan, AL 36303 USA
来源：
EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2004年 / 13卷 / 08期
关键词：
ArcA system; ArcAB system; bacterial cell walls; Escherichia coli; efflux pumps; Gram-negative organisms; Gram-positive organisms; mar operon; multi-drug resistance; protomer; residues; resistant nodulating division; TolC protein; transporter inhibitor complexes; X-ray crystallography;
D O I：
10.1517/13543784.13.8.899
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：899 / 902
页数：4
相关论文
共 50 条
  • [1] Antibiotic resistance caused by gram-negative multidrug efflux pumps
    Nikaido, H
    [J]. CLINICAL INFECTIOUS DISEASES, 1998, 27 : S32 - S41
  • [2] Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance
    Blair, Jessica M. A.
    Richmond, Grace E.
    Piddock, Laura J. V.
    [J]. FUTURE MICROBIOLOGY, 2014, 9 (10) : 1165 - 1177
  • [3] Multidrug efflux pumps of gram-negative bacteria
    Nikaido, H
    [J]. JOURNAL OF BACTERIOLOGY, 1996, 178 (20) : 5853 - 5859
  • [4] Inhibitors of efflux pumps in Gram-negative bacteria
    Pagès, JM
    Masi, M
    Barbe, J
    [J]. TRENDS IN MOLECULAR MEDICINE, 2005, 11 (08) : 382 - 389
  • [5] Extending the Potency and Lifespan of Antibiotics: Inhibitors of Gram-Negative Bacterial Efflux Pumps
    Duffey, Maelle
    Jumde, Ravindra P.
    da Costa, Renata M. A.
    Ropponen, Henni-Karoliina
    Blasco, Benjamin
    Piddock, Laura J. V.
    [J]. ACS INFECTIOUS DISEASES, 2024, 10 (05): : 1458 - 1482
  • [6] Non-antibiotics, Efflux Pumps and Drug Resistance of Gram-negative Rods
    Laudy, Agnieszka Ewa
    [J]. POLISH JOURNAL OF MICROBIOLOGY, 2018, 67 (02) : 129 - 135
  • [7] RND efflux pumps in Gram-negative bacteria; regulation, structure and role in antibiotic resistance
    Colclough, Abigail L.
    Alav, Ilyas
    Whittle, Emily E.
    Pugh, Hannah L.
    Darby, Elizabeth M.
    Legood, Simon W.
    McNeil, Helen E.
    Blair, Jessica M. A.
    [J]. FUTURE MICROBIOLOGY, 2020, 15 (02) : 143 - 157
  • [8] Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria
    Nikaido, Hiroshi
    Pages, Jean-Marie
    [J]. FEMS MICROBIOLOGY REVIEWS, 2012, 36 (02) : 340 - 363
  • [9] Resistance-Nodulation-Division Multidrug Efflux Pumps in Gram-Negative Bacteria: Role in Virulence
    Fernando, Dinesh M.
    Kumar, Ayush
    [J]. ANTIBIOTICS-BASEL, 2013, 2 (01): : 163 - 181
  • [10] Antibiotic efflux pumps in Gram-negative bacteria:: the inhibitor response strategy
    Mahamoud, Abdallah
    Chevalier, Jacqueline
    Alibert-Franco, Sandrine
    Kern, Winfried V.
    Pages, Jean-Marie
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 59 (06) : 1223 - 1229
12345