Comparison of monocyte with high density lipoprotein cholesterol ratio in dipper and nondipper hypertensive patients

被引:15
|
作者
Selcuk, Murat [1 ]
Yildirim, Ersin [2 ]
Saylik, Faysal [1 ]
机构
[1] Univ Hlth Sci, Van Educ & Res Hosp, Dept Cardiol, Van, Turkey
[2] Univ Hlth Sci, Umraniye Educ & Res Hosp, Dept Cardiol, Istanbul, Turkey
关键词
dipper hypertension; HDL-cholesterol; hypertension; monocyte count; nondipper hypertension; CORONARY-ARTERY-DISEASE; BLOOD-PRESSURE; ORGAN DAMAGE; RISK; INDIVIDUALS; PREDICTOR; SEVERITY; EVENTS;
D O I
10.2217/bmm-2019-0062
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Aim: We aimed to compare the monocyte to HDL-cholesterol ratio (MHR) of nondipper hypertension (NDHT) and dipper hypertension patients. Patients & methods: A total of 162 patients were included in the study. Patients were grouped as dipper and nondipper according to 24-h ambulatory blood pressure recordings. Results: The MHR was significantly higher in nondipper hypertension group compared with control (p < 0.001) and dipper hypertension groups (p = 0.03). MHR, hs-CRP and red-cell distribution width (RDW) were independent predictors of nondipper hypertension. Area under the curve was 0.62 (p = 0.034) for MHR and 0.61 (p = 0.012) for hs-CRP in the ROC analysis. Conclusion: MHR has elevated levels in NDHT patients. Increased levels of MHR may evaluate as increased risk of cardiovascular events in NDHT patients.
引用
收藏
页码:1289 / 1296
页数:8
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