NADPH-diaphorase-positive neurons in the auditory cortex of young and old rats

被引:18
|
作者
Ouda, L
Nwabueze-Ogbo, FC
Druga, R
Syka, J
机构
[1] Acad Sci Czech Republ, Inst Expt Med, Prague 14220, Czech Republic
[2] Charles Univ, Dept Funct Anat, Fac Med 2, Prague, Czech Republic
关键词
aging; auditory cortex; NADPH-diaphorase; rat;
D O I
10.1097/01.wnr.0000058243.21747.4d
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Age-related changes in NADPH-diaphorase (NADPH-d)-positive neurons were examined in the auditory cortex of young (3 months old) and very old (36 months old) rats (strain Long Evans). In very old rats a significant reduction was found in the thickness of the auditory cortex, to 54% of that in young animals, as well as changes in the shape and configuration of nerve cell bodies and dendrites. Quantitative analysis demonstrated an age-related increase in the number of dendritic segments and dendritic branching points. The length of dendrites in NADPH-d-positive neurons and their density increased in very old rats. The total number of NADPH-cl-positive neurons within the Te 1 and Te 3 fields was 13% lower in the old rats than in the young.
引用
收藏
页码:363 / 366
页数:4
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