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The Epidural Treatment of Sciatica: Its Origin and Evolution
被引：26
|作者：
Ter Meulen, Bastiaan C.
[1
,4
]
Weinstein, Henry
[1
,4
]
Ostelo, Raymond
[2
,3
]
Koehler, Peter J.
[5
]
机构：
[1] Onze Lieve Vrouw Hosp, Dept Neurol, Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Dept Hlth Sci, Amsterdam, Netherlands
[3] EMGO Inst Hlth & Care Res, Amsterdam, Netherlands
[4] Zaans Med Ctr, Dept Neurol, Zaandam, Netherlands
[5] Atrium Med Ctr, Dept Neurol, Heerlen, Netherlands
关键词：
Back pain;
Sciatica;
Pain treatment;
Epidural injections;
History;
Corticosteroids;
Debate;
STEROID INJECTIONS;
CORTICOSTEROID INJECTION;
COMPLICATIONS;
SAFETY;
PAIN;
CONTROVERSY;
MANAGEMENT;
EFFICACY;
HISTORY;
FOOD;
D O I：
10.1159/000443729
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Epidural injection with corticosteroids is a common treatment option for patients with lower back pain or sciatica. In this paper we review its origin and evolution. The first injections were given around 1900 in Paris by Jean Sicard (1872-1929) and Fernand Cathelin (1873-1945), who worked independently. They both injected small volumes of cocaine into the sacral hiatus. After a slow start, the epidural treatment of back pain and sciatica gradually spread to other parts of Europe and Northern America. In the early 1950s, corticosteroids were introduced for epidural use. Since the 1970s, there have been numerous clinical trials that show a significant, although small, effect of epidural corticosteroid injections compared with placebo for leg pain in the short term. Despite an ongoing debate about effectiveness and safety, epidural injections remain popular. (C) 2016 S. Karger AG, Basel
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页码：58 / 64
页数：7
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