A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer

被引：0
|
作者：
Caputo, Emilia [1 ]
机构：
[1] CNR, Inst Genet & Biophys IGB A Buzzati Traverso, Via Pietro Castellino 111, I-80131 Naples, Italy
来源：
THERANOSTICS | 2017年 / 7卷 / 07期
关键词：
D O I：
10.7150/thno.20460
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Cancer is a very complex disease, where cell alterations (i.e. gene mutations, dysregulated signaling pathway(s) and epigenetic modifications) contribute to its development and progression. Elucidating the connections among these cell modifications is a critical challenge, in order to understand the mechanisms which are activated from cancer cells to survive and proliferate. Interesting, Prof. Peng Hou and colleagues, at the First Affiliated Hospital of Xi'an Jiaotong University in China, identified unknown epigenetic mechanisms and their involvement in the tumorigenesis of B-RAF(V600E)-driven cancer.
引用
收藏
页码：2108 / 2110
页数：3
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