Acute HIV Infections among Men with Genital Ulcer Disease in South Africa

被引：6

作者：

Bailey, G. Paz ^{[1
,2
]}

Sternberg, M. ^{[3
]}

Lewis, D. A. ^{[4
,5
,7
]}

Puren, A. ^{[6
]}

机构：

[1] Del Valle Univ Guatemala, Guatemala City 01015, Guatemala

[2] Ctr Dis Control & Prevent Collaborat, Guatemala City, Guatemala

[3] Ctr Dis Control & Prevent, Natl Ctr HIV STD & TB Prevent, Atlanta, GA USA

[4] Natl Inst Communicable Dis NHLS, STI Reference Ctr, Sandringham, England

[5] Natl Inst Communicable Dis NHLS, STI Reference Ctr, Sandringham, England

[6] Natl Inst Communicable Dis NHLS, Specialized Mol Diagnost Unit, Sandringham, England

[7] Univ Witwatersrand, Dept Internal Med, Johannesburg, South Africa

来源：

JOURNAL OF INFECTIOUS DISEASES | 2010年 / 201卷 / 12期

关键词：

HUMAN-IMMUNODEFICIENCY-VIRUS; TRANSMISSION; MANAGEMENT; STAGE;

D O I：

10.1086/652785

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated acute human immunodeficiency virus (HIV) infection among men enrolled in a genital ulcer treatment trial in South Africa. HIV-negative participants were tested at baseline by HIV RNA polymerase chain reaction and followed up after 1 month to measure HIV seroconversion. There were 228 HIV-negative men at baseline; 10 were positive for HIV RNA, and 8 seroconverted to HIV at day 28. The prevalence of acute HIV among HIV-negative men at baseline was 18 (7.9%) of 228 men (95% confidence interval [CI], 4.4-11.4) and 18 (2.9%) of 615 men (95% CI, 1.6-4.3) in the overall study population. These data highlight the importance of genital ulcer patients in HIV transmission.

引用

页码：1811 / 1815

页数：5

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