Acute HIV Infections among Men with Genital Ulcer Disease in South Africa

被引：6

作者：

Bailey, G. Paz ^{[1
,2
]}

Sternberg, M. ^{[3
]}

Lewis, D. A. ^{[4
,5
,7
]}

Puren, A. ^{[6
]}

机构：

[1] Del Valle Univ Guatemala, Guatemala City 01015, Guatemala

[2] Ctr Dis Control & Prevent Collaborat, Guatemala City, Guatemala

[3] Ctr Dis Control & Prevent, Natl Ctr HIV STD & TB Prevent, Atlanta, GA USA

[4] Natl Inst Communicable Dis NHLS, STI Reference Ctr, Sandringham, England

[5] Natl Inst Communicable Dis NHLS, STI Reference Ctr, Sandringham, England

[6] Natl Inst Communicable Dis NHLS, Specialized Mol Diagnost Unit, Sandringham, England

[7] Univ Witwatersrand, Dept Internal Med, Johannesburg, South Africa

来源：

JOURNAL OF INFECTIOUS DISEASES | 2010年 / 201卷 / 12期

关键词：

HUMAN-IMMUNODEFICIENCY-VIRUS; TRANSMISSION; MANAGEMENT; STAGE;

D O I：

10.1086/652785

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated acute human immunodeficiency virus (HIV) infection among men enrolled in a genital ulcer treatment trial in South Africa. HIV-negative participants were tested at baseline by HIV RNA polymerase chain reaction and followed up after 1 month to measure HIV seroconversion. There were 228 HIV-negative men at baseline; 10 were positive for HIV RNA, and 8 seroconverted to HIV at day 28. The prevalence of acute HIV among HIV-negative men at baseline was 18 (7.9%) of 228 men (95% confidence interval [CI], 4.4-11.4) and 18 (2.9%) of 615 men (95% CI, 1.6-4.3) in the overall study population. These data highlight the importance of genital ulcer patients in HIV transmission.

引用

页码：1811 / 1815

页数：5

共 50 条

[1] Correlates of bacterial ulcers and acute HSV-2 infection among men with genital ulcer disease in South Africa: age, recent sexual behaviours, and HIV
Leichliter, Jami S.
Lewis, David A.
Paz-Bailey, Gabriela
[J]. SOUTHERN AFRICAN JOURNAL OF INFECTIOUS DISEASES, 2016, 31 (02) : 61 - 65
[2] GENITAL ULCER DISEASE IN WOMEN IN DURBAN, SOUTH-AFRICA
OFARRELL, N
HOOSEN, AA
COETZEE, KD
VANDENENDE, J
[J]. GENITOURINARY MEDICINE, 1991, 67 (04): : 322 - 326
[3] Determinants of HIV Type 1 Shedding from Genital Ulcers among Men in South Africa
Paz-Bailey, Gabriela
Sternberg, Maya
Puren, Adrian J.
Steele, Lisa
Lewis, David A.
[J]. CLINICAL INFECTIOUS DISEASES, 2010, 50 (07) : 1060 - 1067
[4] Prevalence and Associations of Genital Ulcer and Urethral Pathogens in Men Presenting With Genital Ulcer Syndrome to Primary Health Care Clinics in South Africa
Lewis, David A.
Mueller, Etienne
Steele, Lisa
Sternberg, Maya
Radebe, Frans
Lyall, Michael
Ballard, Ronald C.
Paz-Bailey, Gabriela
[J]. SEXUALLY TRANSMITTED DISEASES, 2012, 39 (11) : 880 - 885
[5] THE ASSOCIATION BETWEEN GENITAL ULCER DISEASE AND ACQUISITION OF HIV INFECTION IN HOMOSEXUAL MEN
STAMM, WE
HANDSFIELD, HH
ROMPALO, AM
ASHLEY, RL
ROBERTS, PL
COREY, L
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1988, 260 (10): : 1429 - 1433
[6] HIV infections in men in Africa
不详
[J]. BMJ-BRITISH MEDICAL JOURNAL, 2007, 334 (7596): : 713 - 713
[7] Unrecognized genital ulcer disease among rural South African women
Wilkinson, D
Ramjee, G
Sturm, AW
[J]. INTERNATIONAL JOURNAL OF STD & AIDS, 1998, 9 (08) : 494 - 494
[8] The clinical diagnosis of genital ulcer disease in men
DiCarlo, RP
Martin, DH
[J]. CLINICAL INFECTIOUS DISEASES, 1997, 25 (02) : 292 - 298
[9] SOAP AND WATER PROPHYLAXIS FOR LIMITING GENITAL ULCER DISEASE AND HIV-1 INFECTION IN MEN IN SUB-SAHARAN AFRICA
OFARRELL, N
[J]. GENITOURINARY MEDICINE, 1993, 69 (04): : 297 - 300
[10] The changing epidemiology of genital ulcer disease in South Africa: has donovanosis been eliminated?
Muller, Etienne E.
Kularatne, Ranmini
[J]. SEXUALLY TRANSMITTED INFECTIONS, 2020, 96 (08) : 596 - 600

← 1 2 3 4 5 →