Structure of human Niemann-Pick C1 (NPC1) protein and NPC1-NPC2 complex

被引:0
|
作者
Li, Xiaochun [1 ]
机构
[1] Rockefeller Univ, 1230 York Ave, New York, NY 10021 USA
来源
FASEB JOURNAL | 2017年 / 31卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
629.2
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson's disease
    Bencheikh, Bouchra Ouled Amar
    Senkevich, Konstantin
    Rudakou, Uladzislau
    Yu, Eric
    Mufti, Kheireddin
    Ruskey, Jennifer A.
    Asayesh, Farnaz
    Laurent, Sandra B.
    Spiegelman, Dan
    Fahn, Stanley
    Waters, Cheryl
    Monchi, Oury
    Dauvilliers, Yves
    Espay, Alberto J.
    Dupre, Nicolas
    Greenbaum, Lior
    Hassin-Baer, Sharon
    Rouleau, Guy A.
    Alcalay, Roy N.
    Fon, Edward A.
    Gan-Or, Ziv
    NEUROBIOLOGY OF AGING, 2020, 93 : 143.e1 - 143.e4
  • [42] Niemann-Pick type C disease: a novel NPC1 mutation segregating in a Greek island
    Mavridou, I.
    Cozar, M.
    Douzgou, S.
    Xaidara, A.
    Lianou, D.
    Vanier, M. T.
    Dimitriou, E.
    Grinberg, D.
    Vilageliu, L.
    Michelakakis, H.
    CLINICAL GENETICS, 2014, 85 (06) : 543 - 547
  • [43] Ebola viral receptor Niemann–Pick C1 (NPC1) in human cancers: a potential biomarker and immunotherapeutic target
    Zhen Fang
    Peijuan Li
    Liang Shang
    Fei Li
    Human Cell, 2022, 35 : 423 - 426
  • [44] Niemann-Pick Disease Type C: Mutation Spectrum and Novel Sequence Variations in the Human NPC1 Gene
    Márcia Polese-Bonatto
    Hugo Bock
    Ana Carolina S. Farias
    Rafaella Mergener
    Maria Cristina Matte
    Mirela S. Gil
    Felipe Nepomuceno
    Fernanda T. S. Souza
    Rejane Gus
    Roberto Giugliani
    Maria Luiza Saraiva-Pereira
    Molecular Neurobiology, 2019, 56 : 6426 - 6435
  • [45] Niemann-Pick Disease Type C: Mutation Spectrum and Novel Sequence Variations in the Human NPC1 Gene
    Polese-Bonatto, Marcia
    Bock, Hugo
    Farias, Ana Carolina S.
    Mergener, Rafaella
    Matte, Maria Cristina
    Gil, Mirela S.
    Nepomuceno, Felipe
    Souza, Fernanda T. S.
    Gus, Rejane
    Giugliani, Roberto
    Saraiva-Pereira, Maria Luiza
    MOLECULAR NEUROBIOLOGY, 2019, 56 (09) : 6426 - 6435
  • [46] Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis
    Rauniyar, Navin
    Subramanian, Kanagaraj
    Lavallee-Adam, Mathieu
    Martinez-Bartolome, Salvador
    Balch, William E.
    Yates, John R., III
    MOLECULAR & CELLULAR PROTEOMICS, 2015, 14 (07) : 1734 - 1749
  • [47] Modulation of Niemann-Pick C1 like 1 (NPC1L1) protein by cholesterol in Caco2 cells
    Annaba, Fadi
    Sarwar, Zaheer
    Gill, Ravinder K.
    Saksena, Seema
    Pradeep, Dudeja K.
    Alrefai, Waddah A.
    GASTROENTEROLOGY, 2006, 130 (04) : A100 - A100
  • [48] Molecular analysis of NPC1 and NPC2 gene in 34 Niemann-Pick C Italian Patients: identification and structural modeling of novel mutations
    Fancello, Tatiana
    Dardis, Andrea
    Rosano, Camillo
    Tarugi, Patrizia
    Tappino, Barbara
    Zampieri, Stefania
    Pinotti, Elisa
    Corsolini, Fabio
    Fecarotta, Simona
    D'Amico, Adele
    Di Rocco, Maja
    Uziel, Graziella
    Calandra, Sebastiano
    Bembi, Bruno
    Filocamo, Mirella
    NEUROGENETICS, 2009, 10 (03) : 229 - 239
  • [49] Niemann-Pick Type C Disease: A QM/MM Study of Conformational Changes in Cholesterol in the NPC1(NTD) and NPC2 Binding Pockets
    Elghobashi-Meinhardt, Nadia
    BIOCHEMISTRY, 2014, 53 (41) : 6603 - 6614
  • [50] Niemann-Pick C1 disease:: Correlations between NPC1 mutations, levels of NPC1 protein, and phenotypes emphasize the functional significance of the putative sterol-sensing domain and of the cysteine-rich luminal loop
    Millat, G
    Marçais, C
    Tomasetto, C
    Chikh, K
    Fensom, AH
    Harzer, K
    Wenger, DA
    Ohno, K
    Vanier, MT
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 68 (06) : 1373 - 1385