Fluorinated imidazoles as 19F probes for biomimetic studies of heme a3 -: Cub site in cytochrome c oxidase

被引：6
|
作者：
Collman, JP [1 ]
Boulatov, R [1 ]
Sunderland, CJ [1 ]
Zhong, M [1 ]
机构：
[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
来源：
JOURNAL OF FLUORINE CHEMISTRY | 2000年 / 106卷 / 02期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
imidazoles; fluorine compounds; carboxylic acids derivatives; F-19-NMR;
D O I：
10.1016/S0022-1139(00)00328-6
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A series of 4,5-imidazole carboxylic acids bearing fluorinated substituents is synthesized from simple commercially available fluorinated substrates utilizing several different approaches to modify the imidazole core. These imidazole derivatives are specifically designed to be sensitive probes for physicochemical studies of processes in the coordination environments of metals employing F-19-NMR techniques, particularly in the context of our ongoing biomimetic work on imidazole-derivatized porphyrins. (C) 2000 Elsevier Science S.A. All rights reserved.
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页码：189 / 197
页数：9
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