Generation of a human induced pluripotent stem cell line from a patient diagnosed with schizophrenia carrying a 16p11.2 deletion

被引:0
|
作者
Madencioglu, Deniz A. [1 ]
Kruth, Karina [1 ]
Shin, Mallory [2 ]
Andreasen, Nancy [1 ]
Wassink, Thomas [1 ]
Williams, Aislinn [1 ]
机构
[1] Univ Iowa, Iowa Neurosci Inst, Dept Psychiat, Iowa City, IA USA
[2] Univ Iowa, Iowa Neurosci Inst, Dept Pathol, Iowa City, IA USA
关键词
D O I
10.1016/j.scr.2021.102636
中图分类号
Q813 [细胞工程];
学科分类号
摘要
16p11.2 copy number variations have been associated with neurodevelopmental disorders. Human induced pluripotent stem cells were generated from fibroblasts obtained from a patient diagnosed with schizophrenia with a 16p11.2 deletion. The generated cell line was further validated for its pluripotency and potential to differentiate into the three germ layers.
引用
收藏
页数:5
相关论文
共 50 条
  • [41] Generation of a human induced pluripotent stem cell line from a hypertrophic cardiomyopathy patient carrying MYH6 /c.611G > A mutation
    Yang, Zongkuai
    Zhou, Jingjun
    Wang, Hao
    Chen, Xianzhen
    Sun, Yaxun
    Jiang, Chenyang
    Liang, Ping
    STEM CELL RESEARCH, 2024, 81
  • [42] Generation of a human induced pluripotent stem cell line, YCMi002-A, from a Factor VII deficiency patient carrying F7 mutations
    Kim, Do-Hun
    Park, Chul-Yong
    Cho, Sung-Rae
    Kim, Dong-Wook
    STEM CELL RESEARCH, 2020, 49
  • [43] Generation of a human induced pluripotent stem cell line (SBWCHi001-A) from a patient with NEDSDV carrying a pathogenic mutation in CTNNB1 gene
    Yan, Rui
    Liu, Pengyu
    Li, Fake
    Chu, Meng
    Lei, Jiafan
    Wang, Feng
    Luo, Liangping
    Xu, Xueqing
    STEM CELL RESEARCH, 2020, 49
  • [44] Generation of a human induced pluripotent stem cell line (FSMi001-A) from fibroblasts of a patient carrying heterozygous mutation in the REEP1 gene
    Baggiani, Matteo
    Santorelli, Filippo Maria
    Mero, Serena
    Privitera, Flavia
    Damiani, Devid
    Tessa, Alessandra
    STEM CELL RESEARCH, 2024, 79
  • [45] Generation of an induced pluripotent stem cell line from a Kennedy Disease patient with AR mutation
    Zhang, Meng
    Liu, Rui
    Sun, Pengpeng
    Zhang, Chengsen
    Wang, Jingdong
    Li, Changjiang
    STEM CELL RESEARCH, 2025, 83
  • [46] Generation of a human induced pluripotent stem cell line (CMCi002-A) from a patient with Gitelman's syndrome
    Lim, Sun Woo
    Shin, Yoo Jin
    Cui, Sheng
    Ko, Eun Jeong
    Lee, Kang In
    Lee, Jae Young
    Chung, Byung Ha
    Yang, Chul Woo
    STEM CELL RESEARCH, 2020, 49
  • [47] Generation of human induced pluripotent stem cell line from peripheral blood of patient with lymphedema-distichiasis syndrome
    Bialobrzeska, Marta
    Stepniewski, Jacek
    Martyniak, Alicja
    Szuba, Andrzej
    Dulak, Jozef
    STEM CELL RESEARCH, 2025, 85
  • [48] Generation and characterization of a human induced pluripotent stem cell (iPSC) line from a patient with congenital heart disease (CHD)
    Lin, Hui
    Ye, Shi-Qiao
    Xu, Zhao-Hui
    Penaloza, Jacqueline S.
    Aljuhani, Mona
    Vetter, Tatyana
    Zhao, Ming -Tao
    McBride, Kim L.
    STEM CELL RESEARCH, 2022, 65
  • [49] Establishment of an induced pluripotent stem cell (iPSC) line from a patient with Clozapine-responder Schizophrenia
    Marcatili, Matteo
    Marsoner, Fabio
    D'Agostino, Armando
    Karnavas, Thodoris
    Bottai, Daniele
    Scarone, Silvio
    Conti, Luciano
    STEM CELL RESEARCH, 2016, 17 (03) : 630 - 633
  • [50] Generation of a human induced pluripotent stem cell line from a patient with hypomyelinating leukodystrophy 22 (HLD22)
    Ozgoren, Oguz K.
    Sequiera, Glen Lester
    Bardile, Costanza Ferrari
    Gjervan, Sophia C.
    Salman, Areesha
    Lehman, Anna
    Turvey, Stuart E.
    Ross, Colin J. D.
    Stockler, Sylvia
    Pouladi, Mahmoud A.
    STEM CELL RESEARCH, 2023, 71