Generation of a human induced pluripotent stem cell line from a patient diagnosed with schizophrenia carrying a 16p11.2 deletion

被引：0
|
作者：
Madencioglu, Deniz A. [1 ]
Kruth, Karina [1 ]
Shin, Mallory [2 ]
Andreasen, Nancy [1 ]
Wassink, Thomas [1 ]
Williams, Aislinn [1 ]
机构：
[1] Univ Iowa, Iowa Neurosci Inst, Dept Psychiat, Iowa City, IA USA
[2] Univ Iowa, Iowa Neurosci Inst, Dept Pathol, Iowa City, IA USA
来源：
STEM CELL RESEARCH | 2022年 / 59卷
关键词：
D O I：
10.1016/j.scr.2021.102636
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
16p11.2 copy number variations have been associated with neurodevelopmental disorders. Human induced pluripotent stem cells were generated from fibroblasts obtained from a patient diagnosed with schizophrenia with a 16p11.2 deletion. The generated cell line was further validated for its pluripotency and potential to differentiate into the three germ layers.
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页数：5
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