Purpose of review The intrinsic limitations of the current major diagnostic classifications have become increasingly apparent. Several constraints these diagnostic systems impose on clinical practice and research have led to a widespread perception that psychiatry must move beyond the nosologic model embodied in contemporary classifications. Thus, the present review covers the ongoing debate on key conceptual issues that may be relevant for the development of ICD-11 and DSM-V. Recent findings The concepts of validity and utility, as applied to diagnostic classifications, received closer attention recently and attempts were made to better define and contrast them. Against such background, issues like conciliating the multiple purposes of diagnosis, choosing taxonomic strategies and determining the boundaries between and within (subtypes and specifiers) diagnostic categories and thresholds can be properly examined. Recent findings from genetics and neuroscience have added complexity to the already intricate field of mental disorders, raising high hopes of breakthroughs in pathophysiology. This bet on pathophysiology inscribes itself in the perennial debate about the nature of mental disorders and their defining (fundamental) level, which of course has critical implications for the future of psychiatry. Summary Despite considerable scientific advances achieved recently, the challenges faced by psychiatry have only been increasing in complexity. In the present state of affairs, conceptual closure and reductionism possibly represent the most serious risks to be avoided. The review ends by suggesting that methodological pluralism is a necessary condition for building a better psychiatric nosology.
机构:
Univ Western Australia, Ctr Clin Res Neuropsychiat, Sch Psyciat & Clin Neurosci, Perth, WA 6009, AustraliaUniv Western Australia, Ctr Clin Res Neuropsychiat, Sch Psyciat & Clin Neurosci, Perth, WA 6009, Australia
机构:
Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Demjaha, A.
Morgan, K.
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Univ Westminster, Dept Psychol, London W1R 8AL, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Morgan, K.
Morgan, C.
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Kings Coll London, Inst Psychiat, Hlth Serv & Populat Res Dept, Ctr Publ Mental Hlth, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Morgan, C.
Landau, S.
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Kings Coll London, Inst Psychiat, Dept Biostat, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Landau, S.
Dean, K.
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Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Dean, K.
Reichenberg, A.
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Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Reichenberg, A.
Sham, P.
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Univ Hong Kong, LKS Fac Med, State Key Lab Brain & Cognit Sci, Hong Kong, Hong Kong, Peoples R China
Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R ChinaKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Sham, P.
Fearon, P.
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Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Fearon, P.
Hutchinson, G.
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Univ W Indies, Psychiat Unit, St Augustine, Trinidad TobagoKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Hutchinson, G.
Jones, P. B.
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Univ Cambridge, Dept Psychiat, Cambridge, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Jones, P. B.
Murray, R. M.
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Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
Murray, R. M.
Dazzan, P.
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Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England
机构:
Univ Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
VISN 5 Vet Adm, Mental Illness Res Educ & Clin Ctr, Baltimore, MD USAUniv Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
Carpenter, W. T., Jr.
Bustillo, J. R.
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Univ New Mexico, Sch Med, Dept Psychiat, Albuquerque, NM 87131 USAUniv Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
Bustillo, J. R.
Thaker, G. K.
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Univ Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
VISN 5 Vet Adm, Mental Illness Res Educ & Clin Ctr, Baltimore, MD USAUniv Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
Thaker, G. K.
van Os, J.
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Maastricht Univ, Dept Psychiat & Neuropsychol, Maastricht, NetherlandsUniv Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
van Os, J.
Krueger, R. F.
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Inst Psychiat, Div Psychol Med, London, England
Washington Univ, Dept Psychol, St Louis, MO 63130 USA
Washington Univ, Dept Psychiat, St Louis, MO 63130 USAUniv Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
Krueger, R. F.
Green, M. J.
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Univ New S Wales, Sch Psychiat, Black Dog Inst, Sydney, NSW, AustraliaUniv Maryland, Sch Med, Maryland Psychiat Res Ctr, Baltimore, MD 21228 USA
机构:
Brigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Dana Farber Canc Inst, Ctr Psychooncol & Palliat Care Res, Boston, MA 02115 USA
Harvard Univ, Sch Med, Ctr Palliat Care, Boston, MA USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Prigerson, Holly G.
Horowitz, Mardi J.
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Univ Calif San Francisco, Sch Med, Dept Psychiat, San Francisco, CA 94143 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Horowitz, Mardi J.
Jacobs, Selby C.
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Yale Univ, Sch Med, Dept Psychiat, New Haven, CT USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Jacobs, Selby C.
Parkes, Colin M.
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St Christophers Hosp, Sydenham, England
St Josephs Hosp, Hackney, EnglandBrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Parkes, Colin M.
Aslan, Mihaela
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Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06510 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Aslan, Mihaela
Goodkin, Karl
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Cedars Sinai Med Ctr, Dept Psychiat & Behav Neurosci, Los Angeles, CA 90048 USA
Univ Calif Los Angeles, David Geffen Sch Med, Dept Psychiat & Behav Sci, Los Angeles, CA 90095 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Goodkin, Karl
Raphael, Beverley
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Univ Western Sydney, Sch Med, Dept Populat Mental Hlth & Disasters, Penrith, NSW 1797, AustraliaBrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Raphael, Beverley
Marwit, Samuel J.
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Univ Missouri, Dept Psychol, St Louis, MO 63121 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Marwit, Samuel J.
Wortman, Camille
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SUNY Stony Brook, Dept Psychol, Stony Brook, NY 11794 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Wortman, Camille
Neimeyer, Robert A.
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Univ Memphis, Dept Psychol, Memphis, TN 38152 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Neimeyer, Robert A.
Bonanno, George A.
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Columbia Univ, Teachers Coll, Dept Counseling & Clin Psychol, New York, NY 10027 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Bonanno, George A.
Block, Susan D.
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Brigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Dana Farber Canc Inst, Ctr Psychooncol & Palliat Care Res, Boston, MA 02115 USA
Harvard Univ, Sch Med, Ctr Palliat Care, Boston, MA USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Block, Susan D.
Kissane, David
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Mem Sloan Kettering Canc Ctr, Dept Psychiat & Behav Sci, New York, NY 10021 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Kissane, David
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Boelen, Paul
Maercker, Andreas
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Univ Zurich, Dept Clin Psychol, Zurich, SwitzerlandBrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Maercker, Andreas
Litz, Brett T.
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Vet Affairs Boston Healthcare Syst, Boston, MA USA
Natl Ctr PTSD, Boston, MA USA
Boston Univ, Sch Med, Boston, MA 02118 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Litz, Brett T.
Johnson, Jeffrey G.
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Columbia Univ, Dept Psychiat, New York, NY USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Johnson, Jeffrey G.
First, Michael B.
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Columbia Univ, Dept Psychiat, New York, NY USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
First, Michael B.
Maciejewski, Paul K.
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Brigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
Dana Farber Canc Inst, Ctr Psychooncol & Palliat Care Res, Boston, MA 02115 USABrigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
机构:
Kings Coll London, Inst Psychiat, London SE5 8AF, EnglandKings Coll London, Inst Psychiat, London SE5 8AF, England
Goldberg, D. P.
Krueger, R. F.
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Washington Univ, Dept Psychol, St Louis, MO 63130 USA
Washington Univ, Dept Psychiat, St Louis, MO 63130 USAKings Coll London, Inst Psychiat, London SE5 8AF, England
Krueger, R. F.
Andrews, G.
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Univ New S Wales, Sch Psychiat, Sydney, NSW, AustraliaKings Coll London, Inst Psychiat, London SE5 8AF, England
Andrews, G.
Hobbs, M. J.
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Univ New S Wales, Sch Psychiat, Sydney, NSW, AustraliaKings Coll London, Inst Psychiat, London SE5 8AF, England